Results 41 to 50 of about 1,525,366 (267)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

The earliest Old Norse metrics

open access: yesFilologia Germanica
This article explores Old Norse metrical developments in the ninth century, focusing on the only securely datable evidence we have: the Rök stanza and Bragi’s poetry.
MIKAEL MALES
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Business Intelligence Systems Accounting Integration in Romania. a Comparative Analysis

open access: yesStudies and Scientific Researches: Economics Edition, 2010
Business Intelligence (BI) systems have penetrated the Romanian market, providing a real decision support by integrating and synthesizing a large variety of information available in real time, anywhere in the world, including through mobile terminals ...
Daniela Postolache (Males)
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

GONORRHEA IN THE MALE. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1898
Gonorrhea is an acute, specific, infectious, systemic disease, with a local manifestation and systemic reaction. I am well aware that this statement is in variance with the almost universal statement of authors, but not so completely so with the clinician and more especially with the patient or victim. The victim of this disease, if allowed to tell his
openaire   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

In Praise of divinatio. The Value of “True Errors” and Metrical Heuristics

open access: yesAnnali Online dell'Università di Ferrara. Sezione Lettere
This article argues that the importance of conjecture, or divinatio, has been downplayed in the mainstream discourse on textual criticism, which has increasingly come to focus on stemmatology alone.
Mikael Males
doaj   +1 more source

Accounting Practice and Intelligent Technologies

open access: yesStudies and Scientific Researches: Economics Edition, 2012
was to determine how intelligent technologies can support accounting practice. Our research allowed for establishment of accounting information intelligent systems typology and for placement of these solutions in the sphere of artificial intelligence ...
Daniela Postolache (Males)
doaj   +1 more source

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