Results 51 to 60 of about 33,897 (290)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Histopathological Analysis of Dens Invaginatus in an Immature Permanent Incisor [PDF]

Journal of Clinical and Diagnostic Research, 2018
Dens Invaginatus (DI) is a congenital development malformation. The complex anatomy of DI aids in the retention of food and bacteria, which leads to pulp necrosis and develops into periapical inflammation. The histopathology of DI is not very clear. This
Liming Jiang, Xuejuan Ma, Yao Liu, Ming Zhong, Xu Chen   +4 more
doaj   +1 more source

Effects of exogenous paclobutrazol and sampling time on the efficiency of in vitro embryo rescue in the breeding of new seedless grape varieties

Journal of Integrative Agriculture, 2022
Embryo rescue technology plays an important role in seedless grape breeding. However, the efficiency of embryo rescue, including the embryo formation, germination, and seedling rates, is closely related to the parental genotypes, degree of abortion ...
Teng-fei XU, Yu-rui GUO, Wen-yuan WANG, Xiao-jian YUAN, Yan-nan CHU, Xiao-wei WANG, Yu-lei HAN, Yue-jin WANG, Rui SONG, Yu-lin FANG, Lu-jun WANG, Yan XU   +11 more
doaj   +1 more source

Natural Intrauterine Infection with Schmallenberg Virus in Malformed Newborn Calves

Emerging Infectious Diseases, 2014
We surveyed morphologic alterations in calves in Belgium that were naturally infected in utero by Schmallenberg virus (SBV) and born with deformities during January–March 2012. SBV-specific RNA was distributed unevenly in different tissues.
C. Bayrou, M. Garigliany, Michaël Sarlet, A. Sartelet, D. Cassart, D. Desmecht   +5 more
semanticscholar   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

[Cavernous malformations].

Der Radiologe, 2008
Cavernomas of the CNS may involve brain parenchyma as well as the spinal cord and belong to those cerebrovascular malformations that have no arteriovenous shunt and thus are generally angiographically occult. Contrary to computed tomography (CT), which is generally suited to reveal calcifications or acute bleeding, magnetic resonance imaging (MRI ...
Ahlhelm, F, Hagen, T, Schulte-Altedorneburg, G, Grunwald, I, Reith, W, Roth, C   +5 more
openaire   +3 more sources

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Salvaging A Hopeless Tooth: Intentional Replantation To Rescues Lateral Incisor

International Dental Journal
Introduction: Intentional replantation (IR) was used to successfully treat a maxillary lateral incisor (#22) that had failed periodontal therapy and conventional endodontic retreatment because to deep palatogingival groove and chronic apical ...
Huichun Liu, Bo Zeng, Xiaomin Lv
doaj   +1 more source