Results 51 to 60 of about 53,238 (306)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Histology and chronological magnetic resonance images of congenital spinal deformity: An experimental study in mice model

open access: yesBMC Musculoskeletal Disorders
Background The natural history of the congenital spinal deformity and its clinical magnitude vary widely in human species. However, we previously reported that the spinal deformities of congenital scoliosis mice did not progress throughout our ...
Haruki Ueda   +6 more
doaj   +1 more source

Using patterns in the automatic marking of ER-Diagrams [PDF]

open access: yes, 2006
This paper illustrates how the notion of pattern can be used in the automatic analysis and synthesis of diagrams, applied particularly to the automatic marking of ER-diagrams.
Burstein J.   +10 more
core   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

The HSS/SNiC : a conceptual framework for collapsing security down to the physical layer [PDF]

open access: yes, 2008
This work details the concept of a novel network security model called the Super NIC (SNIC) and a Hybrid Super Switch (HSS). The design will ultimately incorporate deep packet inspection (DPI), intrusion detection and prevention (IDS/IPS) functions, as ...
Binns, Richard   +2 more
core  

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Toward the automated assessment of entity-relationship diagrams [PDF]

open access: yes, 2004
The need to interpret imprecise diagrams (those with malformed, missing or extraneous features) occurs in the automated assessment of diagrams. We outline our proposal for an architecture to enable the interpretation of imprecise diagrams.
Smith, Neil, Thomas, Pete, Waugh, Kevin
core   +3 more sources

[Cavernous malformations].

open access: yesDer Radiologe, 2008
Cavernomas of the CNS may involve brain parenchyma as well as the spinal cord and belong to those cerebrovascular malformations that have no arteriovenous shunt and thus are generally angiographically occult. Contrary to computed tomography (CT), which is generally suited to reveal calcifications or acute bleeding, magnetic resonance imaging (MRI ...
Ahlhelm, F   +5 more
openaire   +3 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Cross-Composition: A New Technique for Kernelization Lower Bounds [PDF]

open access: yes, 2010
We introduce a new technique for proving kernelization lower bounds, called cross-composition. A classical problem L cross-composes into a parameterized problem Q if an instance of Q with polynomially bounded parameter value can express the logical OR of
Bodlaender, Hans L.   +2 more
core   +5 more sources

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