Results 131 to 140 of about 1,560,230 (391)
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
Parasite Immunology, 2009 SummaryIt has been estimated that chronic infections with viruses, bacteria and parasites contribute to 17·8% of the global burden of cancer, although only a relatively small proportion of the infection‐related cancers can be attributed to helminth infections.
Vennervald, B. J., Polman, K.
openaire +5 more sources
ACANTHOSIS NIGRICANS AS AN INDICATION OF INTERNAL MALIGNANCY [PDF]
, 1915 A. J. MARKLEY
openalex +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
Hypercalcemia of malignancy and new treatment options
Therapeutics and Clinical Risk Management, 2015 Hypercalcemia of malignancy affects up to one in five cancer patients during the course of their disease. It is associated with both liquid malignancies, commonly multiple myeloma, leukemia, and non-Hodgkins lymphoma and solid cancers, particularly ...
Hillel Sternlicht, I. Glezerman
semanticscholar +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Carcinoma of the pancreas. Effect of histological type and grade of malignancy on its behavior [PDF]
, 1951 John Ralph Miller +2 more
openalex +1 more source
The role of fibroblast activation protein in health and malignancy
Cancer Metastasis Review, 2020 Allison A. Fitzgerald, L. Weiner
semanticscholar +1 more source