Results 21 to 30 of about 714,849 (299)

Dermatomyositis and Malignancy

Journal of Investigative Dermatology, 1993
During the past 12 years, many studies applying strict diagnostic criteria have been published that have attempted to settle the controversy about the reality of the association between dermatomyositis and malignancy. Although retrospective, recent studies have shown an increased incidence of malignancy among patients with dermatomyositis when compared
Jean-Marie Bonnetblanc, Philippe Bernard
openaire   +3 more sources

Haploidentical transplantation using posttransplant cyclophosphamide as GVHD prophylaxis in patients over age 70

Blood Advances, 2019
: Hematologic malignancies in older people are unlikely to be cured with chemotherapy alone. Advances in allogeneic blood or marrow transplantation (alloBMT), especially nonmyeloablative (NMA) conditioning and the use of haploidentical donors, now make ...
Philip H. Imus, Hua-Ling Tsai, Leo Luznik, Ephraim J. Fuchs, Carol Ann Huff, Douglas E. Gladstone, Patrick Lowery, Richard F. Ambinder, Ivan M. Borrello, Lode J. Swinnen, Nina Wagner-Johnston, Christian B. Gocke, Syed Abbas Ali, F.Javier Bolaños-Meade, Ravi Varadhan, Richard J. Jones   +15 more
doaj   +1 more source

The roles of metabolic profiles and intracellular signaling pathways of tumor microenvironment cells in angiogenesis of solid tumors

Cell Communication and Signaling, 2022
Innate and adaptive immune cells patrol and survey throughout the human body and sometimes reside in the tumor microenvironment (TME) with a variety of cell types and nutrients that may differ from those in which they developed.
Hamidreza Zalpoor, Fatemeh Aziziyan, Mahsa Liaghat, Maryam Bakhtiyari, Abdullatif Akbari, Mohsen Nabi-Afjadi, Razieh Forghaniesfidvajani, Nima Rezaei   +7 more
doaj   +1 more source

Clinical Manifestations of Kaposi Sarcoma Herpesvirus Lytic Activation: Multicentric Castleman Disease (KSHV–MCD) and the KSHV Inflammatory Cytokine Syndrome

Frontiers in Microbiology, 2012
Soon after the discovery of Kaposi sarcoma (KS)-associated herpesvirus (KSHV), it was appreciated that this virus was associated with most cases of multicentric Castleman disease (MCD) arising in patients infected with human immunodeficiency virus.
Mark N. Polizzotto, Thomas S. Uldrick, Duosha Hu, Robert Yarchoan   +3 more
doaj   +1 more source

Absence of high-grade cervical intraepithelial neoplasia in conization specimens from patients with colposcopic biopsy-confirmed high-grade cervical intraepithelial neoplasia: Retrospective study of 1695 cases

Frontiers in Oncology, 2022
Few studies have investigated the absence of high-grade cervical intraepithelial neoplasia (CIN) in excised specimens, and sample sizes of these studies were limited.
Yulin Guo, Yulin Guo, Ying Wang, Ying Wang, Qiuzi Peng, Qiuzi Peng, Lu Li, Lu Li, Miao Zou, Miao Zou, Chaonan Wang, Chaonan Wang, Xufeng Wu, Xufeng Wu, Quanfu Ma, Quanfu Ma   +15 more
doaj   +1 more source

Daratumumab induces cell-mediated cytotoxicity of primary effusion lymphoma and is active against refractory disease

OncoImmunology, 2023
Primary effusion lymphoma (PEL), an aggressive non-Hodgkin lymphoma caused by Kaposi sarcoma-associated herpesvirus (KSHV), lacks standard therapy and has a median survival of 10–22 months with combination chemotherapy. PEL is a tumor of plasmablast-like
Prabha Shrestha, Yana Astter, David A. Davis, Ting Zhou, Constance M. Yuan, Ramya Ramaswami, Hao-Wei Wang, Kathryn Lurain, Robert Yarchoan   +8 more
doaj   +1 more source

Malignant hyperthermia [PDF]

Orphanet Journal of Rare Diseases, 2007
Malignant hyperthermia (MH) is a pharmacogenetic disorder of skeletal muscle that presents as a hypermetabolic response to potent volatile anesthetic gases such as halothane, sevoflurane, desflurane and the depolarizing muscle relaxant succinylcholine, and rarely, in humans, to stresses such as vigorous exercise and heat.
Pollock Neil, James Danielle, Davis Mark, Rosenberg Henry, Stowell Kathryn   +4 more
openaire   +3 more sources

Improved outcomes of acute lymphoblastic leukemia after allogeneic blood or marrow transplantation with high-dose post-transplantation cyclophosphamide in the era of more effective pre-transplant therapy

Haematologica
The therapeutic landscape in ALL has changed dramatically over the last decade. Allogeneic blood or marrow transplantation (AlloBMT) has also evolved and remains an important option for consolidation.
Jonathan A. Webster, Madison Reed, Hua-Ling Tsai, Philip H. Imus, Douglas B. Smith, Alexander J. Ambinder, Mark J. Levis, Amy E. DeZern, Gabrielle T. Prince, Tania Jain, Javier Bolaños-Meade, Lukasz P. Gondek, Gabriel Ghiaur, William Brian Dalton, Theodoros Karantanos, Suman Paul, Ephraim J. Fuchs, Cole Sterling, Lode J. Swinnen, Nina Wagner-Johnston, Richard F. Ambinder, Christian B. Gocke, Syed Abbas Ali, Carol Ann Huff, Leo Luznik, Ravi Varadhan, Richard J. Jones, Ivana Gojo   +27 more
doaj   +1 more source

Risk factors of acute renal impairment after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

International Journal of Hyperthermia, 2020
Background Acute renal impairment (ARI) is a major complication after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) for cancer patients with peritoneal metastases.
Chao-Yu Chen, Hung-Yu Chang, Chang-Hsien Lu, Min-Chi Chen, Tzu-Hao Huang, Li-Wen Lee, Yu-San Liao, Vincent Chin-Hung Chen, Wen-Shih Huang, Yu-Che Ou, Feng-Chi Lung, Ting-Yao Wang   +11 more
doaj   +1 more source

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

FEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi, Takehiro Suzuki, Ryota Kawahara, Natsumi Harai, Naoshi Dohmae, Siro Simizu   +5 more
wiley   +1 more source