Results 21 to 30 of about 654,876 (248)

Regulation of the Dimerization and Activity of SARS-CoV-2 Main Protease through Reversible Glutathionylation of Cysteine 300

mBio, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent for coronavirus disease 2019 (COVID-19), encodes two proteases required for replication.
David A. Davis, Haydar Bulut, Prabha Shrestha, Amulya Yaparla, Hannah K. Jaeger, Shin-ichiro Hattori, Paul T. Wingfield, John J. Mieyal, Hiroaki Mitsuya, Robert Yarchoan   +9 more
doaj   +1 more source

The roles of metabolic profiles and intracellular signaling pathways of tumor microenvironment cells in angiogenesis of solid tumors

Cell Communication and Signaling, 2022
Innate and adaptive immune cells patrol and survey throughout the human body and sometimes reside in the tumor microenvironment (TME) with a variety of cell types and nutrients that may differ from those in which they developed.
Hamidreza Zalpoor, Fatemeh Aziziyan, Mahsa Liaghat, Maryam Bakhtiyari, Abdullatif Akbari, Mohsen Nabi-Afjadi, Razieh Forghaniesfidvajani, Nima Rezaei   +7 more
doaj   +1 more source

Malignant hyperthermia

Swiss Medical Weekly, 2012
Malignant hyperthermia (MH) is a subclinical myopathy, usually triggered by volatile anaesthetics and depolarising muscle relaxants. Clinical symptoms are variable, and the condition is sometimes difficult to identify. Nevertheless, rapid recognition and specific as well as symptomatic treatment are crucial to avoid a lethal outcome.
Bandschapp, O., Girard, T.
openaire   +4 more sources

Malignant Craniopharyngioma

Archives of Pathology & Laboratory Medicine, 1999
Abstract Craniopharyngiomas are histologically and cytologically benign epithelial tumors of the central nervous system that may be locally aggressive and tend to recur after excision. Malignant change in craniopharyngiomas is extremely rare; we found only 4 such reports in the literature.
T, Kristopaitis, C, Thomas, G J, Petruzzelli, J M, Lee   +3 more
openaire   +2 more sources

Improved outcomes of acute lymphoblastic leukemia after allogeneic blood or marrow transplantation with high-dose post-transplantation cyclophosphamide in the era of more effective pre-transplant therapy

Haematologica
The therapeutic landscape in ALL has changed dramatically over the last decade. Allogeneic blood or marrow transplantation (AlloBMT) has also evolved and remains an important option for consolidation.
Jonathan A. Webster, Madison Reed, Hua-Ling Tsai, Philip H. Imus, Douglas B. Smith, Alexander J. Ambinder, Mark J. Levis, Amy E. DeZern, Gabrielle T. Prince, Tania Jain, Javier Bolaños-Meade, Lukasz P. Gondek, Gabriel Ghiaur, William Brian Dalton, Theodoros Karantanos, Suman Paul, Ephraim J. Fuchs, Cole Sterling, Lode J. Swinnen, Nina Wagner-Johnston, Richard F. Ambinder, Christian B. Gocke, Syed Abbas Ali, Carol Ann Huff, Leo Luznik, Ravi Varadhan, Richard J. Jones, Ivana Gojo   +27 more
doaj   +1 more source

Utility of Computed Tomography Surveillance of Asymptomatic Infection in Children and Young Adults Before Allogeneic Hematopoietic Stem Cell Transplant

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Asymptomatic infection poses a significant risk for children undergoing hematopoietic stem cell transplantation (HSCT). Pre‐transplant surveillance computed tomography (CT) is commonly used to identify occult infection, though its diagnostic yield remains uncertain.
Tyler Obermark, Pradipta Debnath, Rama S. Ayyala, Lara A. Danziger‐Isakov, Jane Koo, Kasiani C. Myers, William R. Otto, Aki Tanimoto, Andrew T. Trout, Cara E. Morin   +9 more
wiley   +1 more source

Imaging of High‐Risk Neuroblastoma: Recommendations From SIOPEN Radiology and Nuclear Medicine Specialty Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij, Catia Olianti, Herve Brisse, Pier Luigi Di Paolo, Maria Garganese, Tejas Kapadia, Jurgen Schaefer, Hugh Wallace, Simon Wan, Bart de Keizer, Irmina Sefic Pasic, Julian Rogasch   +11 more
wiley   +1 more source

Effective management of a rare case of primary renal intravascular large B-cell lymphoma with modified R-CHOP regimen: A case report

SAGE Open Medical Case Reports
Intravascular large B-cell lymphoma, known for its diverse organ involvement, presents significant diagnostic challenges, particularly when it affects the kidneys. This report highlights a rare case of primary renal intravascular large B-cell lymphoma in
Xianbo Huang, Xianhui Wu, Shasha Wang, Chen Mei, Yu Xu, Yanling Ren, Jie Jin, Hongyan Tong, Jiejing Qian   +8 more
doaj   +1 more source

Risk factors of acute renal impairment after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

International Journal of Hyperthermia, 2020
Background Acute renal impairment (ARI) is a major complication after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) for cancer patients with peritoneal metastases.
Chao-Yu Chen, Hung-Yu Chang, Chang-Hsien Lu, Min-Chi Chen, Tzu-Hao Huang, Li-Wen Lee, Yu-San Liao, Vincent Chin-Hung Chen, Wen-Shih Huang, Yu-Che Ou, Feng-Chi Lung, Ting-Yao Wang   +11 more
doaj   +1 more source

Absence of high-grade cervical intraepithelial neoplasia in conization specimens from patients with colposcopic biopsy-confirmed high-grade cervical intraepithelial neoplasia: Retrospective study of 1695 cases

Frontiers in Oncology, 2022
Few studies have investigated the absence of high-grade cervical intraepithelial neoplasia (CIN) in excised specimens, and sample sizes of these studies were limited.
Yulin Guo, Yulin Guo, Ying Wang, Ying Wang, Qiuzi Peng, Qiuzi Peng, Lu Li, Lu Li, Miao Zou, Miao Zou, Chaonan Wang, Chaonan Wang, Xufeng Wu, Xufeng Wu, Quanfu Ma, Quanfu Ma   +15 more
doaj   +1 more source