Results 141 to 150 of about 31,799 (185)
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Therapy of the Malignant Carcinoid Syndrome
Annals of Internal Medicine, 1965Excerpt The therapy of the malignant carcinoid syndrome presents a unique challenge to physicians caring for patients with this unusual disease.
Charles E Mengel
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Treatment of the carcinoid tumor and the malignant carcinoid syndrome.
Journal of Clinical Oncology, 1983 Certainly in treatment of the carcinoid tumor surgery has a well-established curative and palliative potential. The primary challenge is a knowledgable marriage between stage of disease and aggressiveness of operative procedure. Nonsurgical treatment of the malignant disease per se has thus far not produced optimum results and, in the opinion of this ...
C G Moertel
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Cutaneous manifestations of the malignant carcinoid syndrome
British Journal of Dermatology, 2005The incidence of carcinoid tumours is approximately 1.5 per 100 000 of the population. The malignant carcinoid syndrome, which is caused by circulating neuroendocrine mediators produced by the tumour, occurs in less than 10% of patients. Cutaneous involvement, although recognized in this rare syndrome, has rarely been reported.To examine a series of ...
G J Poston, J Vora, N J Wilson
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Results of Pharmacologic Treatment in the Malignant Carcinoid Syndrome
New England Journal of Medicine, 1962THE patient with the malignant carcinoid syndrome is confronted with a group of uncomfortable and debilitating symptoms. These may include recurrent acute flushing, colicky abdominal pains, violent and profuse watery diarrhea, tachycardia, asthma-like wheezing and, less often, profound weakness, depression or agitation, dyspnea and dependent edema ...
Michael Murray
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Malignant carcinoid syndrome: Two case reports
Journal of Surgical Oncology, 1980AbstractThe malignant carcinoid syndrome (MCS) is a rare complication of malignant carcinoid neoplasms, fewer than 200 cases having been reported since its description by Thorson in 1954. Its signs and symptoms vary with the site of the primary neoplasm, and MCS is now recognized as one member of the large family of endocrine tumors ‐ APUDOMAS ...
J L, Spann, D, Van Wormer, M E, Sandlin
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Archives of Internal Medicine, 1966 SINCE the early descriptions of the carcinoid syndrome, 1-4 it has been assumed that the associated hyperserotonemia is responsible for the symptoms and development of the cardiac lesions. These lesions, which appear mainly on the right side of the heart, are characterized by subendocardial proliferation of fibrous tissue resulting in thickening of the
ARNOLD ADICOFF
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Diagnosis and Treatment of Malignant Carcinoid Syndrome
JAMA - Journal of the American Medical Association, 1974THE malignant carcinoid syndrome has challenged the skills of the clinician, biochemist, and pharmacologist since its original description by Biorck et al 1 22 years ago. Although attention originally centered on a symptom complex and a serotonin-producing midintestinal neoplasm that had metastasized to the liver, the carcinoid syndrome has now been ...
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Cancer, 1991
Sixteen patients with metastatic neuroendocrine tumors and the malignant carcinoid syndrome were treated with cyproheptadine (Periactin, Merck, Sharp & Dohme, West Point, PA) at maximum tolerable doses that ranged from 12 to 48 mg daily. Usual side effects were mild sedation and dry mouth, but three patients found it impossible to sustain treatment due
Charles G Moertel +2 more
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Sixteen patients with metastatic neuroendocrine tumors and the malignant carcinoid syndrome were treated with cyproheptadine (Periactin, Merck, Sharp & Dohme, West Point, PA) at maximum tolerable doses that ranged from 12 to 48 mg daily. Usual side effects were mild sedation and dry mouth, but three patients found it impossible to sustain treatment due
Charles G Moertel +2 more
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The malignant carcinoid syndrome
The American Journal of Digestive Diseases, 1966exaly +3 more sources
Treatment of the Malignant Carcinoid Syndrome
New England Journal of Medicine, 1986Larry K Kvols +2 more
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