Year in Review 2018 by the Brazilian Gastrointestinal Tumors Group: Neuroendocrine Tumors
Neuroendocrine tumors (NET) constitute a heterogeneous group of neoplasms with variable prognoses and clinical presentations. Therefore their therapeutic management is challenging, involving a real multidisciplinary approach composed of medical ...
Duilio R. Rocha +2 more
doaj +1 more source
Pioglitazone inhibits growth of carcinoid cells and promotes TRAIL-induced apoptosis by induction of p21(waf1/cip1) [PDF]
Background/Aims: We investigated the effect of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) agonist pioglitazone on growth and TRAIL-induced apoptosis in carcinoid cells.
Chen, Youhai +4 more
core +1 more source
Hormonal crises following receptor radionuclide therapy with the radiolabeled somatostatin analogue [177Lu-DOTA0,Tyr 3]octreotate [PDF]
Introduction: Receptor radionuclide therapy is a promising treatment modality for patients with neuroendocrine tumors for whom alternative treatments are limited.
Aken, M.O. (Maarten) van +7 more
core +1 more source
Somatostatin receptor scintigraphy in patients with carcinoid tumors [PDF]
In 80% to 90% of patients with carcinoids, tumor sites can be detected with [111In-DTPA-D-Phe1]-octreotide scintigraphy. Unexpected, additional localizations are reported in one-third to two-thirds of patients.
Krenning, E.P. (Eric) +1 more
core +7 more sources
Unicentric castleman disease complicated by paraneoplastic bronchiolitis obliterans and pemphigus
Bronchiolitis obliterans (BO) and paraneoplastic pemphigus are rare and ominous complications of Castleman disease. Collectively, these processes have been reported as part of paraneoplastic autoimmune multiorgan syndrome (PAMS), and they can occur in ...
Hassan A. Raza, MD. +6 more
doaj +1 more source
Primary renal teratoma: a rare entity [PDF]
: Teratomas are neoplasms that arise from pluripotent cells and can differentiate along one or more embryonic germ lines. Renal teratoma is an exceedingly rare condition.
Afaf Amarti +7 more
core +1 more source
Paraneoplastic cerebellar degeneration associated with lymphoepithelial carcinoma of the tonsil [PDF]
Background: Paraneoplastic cerebellar degeneration (PCD) is a classical tumor-associated, immune-mediated disease typically associated with gynecological malignancies, small-cell lung-cancer or lymphoma.
Hartmann, Sylvia +5 more
core +1 more source
Telotristat ethyl in carcinoid syndrome: safety and efficacy in the TELECAST phase 3 trial [PDF]
Telotristat ethyl, a tryptophan hydroxylase inhibitor, was efficacious and well tolerated in the phase 3 TELESTAR study in patients with carcinoid syndrome (CS) experiencing ≥4 bowel movements per day (BMs/day) while on somatostatin analogs (SSAs ...
Anthony, Lowell B. +17 more
core +2 more sources
Pancreatic tumors imaging: an update [PDF]
Currently, ultrasound (US), computed tomography (CT) and Magnetic Resonance imaging (MRI) represent the mainstay in the evaluation of pancreatic solid and cystic tumors affecting pancreas in 80-85% and 10-15% of the cases respectively. Integration of US,
Baccari, Paolo +8 more
core +1 more source
Multiple endocrine neoplasia type 1 (MEN1) is a rare hereditary tumor syndrome inherited in an autosomal dominant manner and characterized by a predisposition to a multitude of endocrine neoplasms primarily of parathyroid, enteropancreatic, and anterior ...
Crystal D. C. Kamilaris +1 more
doaj +1 more source

