Results 161 to 170 of about 478,842 (334)
Local recurrence of choroidal malignant melanoma following enucleation. [PDF]
, 1981 Robert F. Sanke +3 more
openalex +1 more source
Advanced Science, EarlyView.In hepatocellular carcinoma (HCC), aberrantly activated Notch1 signaling induces its target gene YY1, which impairs immunotherapy efficacy by suppressing tumor cell‐ICAM1‐driven T cell activation and the mediated pyroptosis of T cells against tumor cells.
Ke Zhu +10 more
wiley +1 more source
Malignant Melanoma in the Anterior Region of Maxillary Gingiva: A Rare Case Report
, 2015 Rajesh Twyana +3 more
openalex +2 more sources
A Case of Primary Malignant Melanoma of the Palatine Tonsil [PDF]
, 2015 Milan Milojevic +5 more
openalex +1 more source
TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy
Advanced Science, EarlyView.We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng +9 more
wiley +1 more source
Advanced Science, EarlyView.This study demonstrates that dual UCP2/IL‐17 blockade reprograms T‐cell metabolism to overcome PDAC immunosuppression. Genipin‐mediated UCP2 inhibition enhances CD8⁺ T‐cell IFN‐γ via IL‐12R/STAT4/mTOR signaling and mitochondrial OXPHOS. Combined IL‐17 depletion amplifies Tc1/Th1 responses, reduces MDSCs, and prolongs survival in PDAC models ...
Chuan‐Teng Liu +11 more
wiley +1 more source
Supplementary Table S1 from Targeting Akt3 Signaling in Malignant Melanoma Using Isoselenocyanates [PDF]
, 2023 Arati Sharma +7 more
openalex +1 more source