Results 21 to 30 of about 476,450 (235)
AbstractContext.—The rapidly developing fields of melanoma research are revolutionizing the current concepts on melanoma etiology and pathogenesis and are introducing newer diagnostic techniques and potential therapeutic approaches.Objectives.—To present the most current concepts on the etiology and pathogenesis of melanoma and to introduce the recent ...
A, Slominski +5 more
openaire +2 more sources
Harnessing autophagy to overcome mitogen‐activated protein kinase kinase inhibitor‐induced resistance in metastatic melanoma [PDF]
Background Patients with malignant melanoma often relapse after treatment with BRAF and/or mitogen‐activated protein kinase kinase (MEK) inhibitors (MEKi) owing to development of drug resistance.
Alexander, M. +6 more
core +1 more source
Primary retroperitoneal malignant melanoma
Malignant melanoma is a tumour arising from the melancytes which are derived from the neural crest, it migrate during the embryological development and may be found in the non cutoneons site.
Aziz Zentar +8 more
doaj +1 more source
Long-term Survival after Metastatic Childhood Melanoma
Summary: Malignant melanoma in children is very rare and accounts for only 1–3% of all melanomas. A congenital melanocytic nevus depending on the size of the lesion is one of the risk factors for developing childhood melanoma because of the possible ...
Anne Kristine Larsen, MD +2 more
doaj +1 more source
Melanoma mimicking malignant peripheral nerve sheath tumor with spread to the cerebellopontine angle: Utility of next-generation sequencing in diagnosis [PDF]
Cutaneous spindle cell malignancy is associated with a broad differential diagnosis, particularly in the absence of a known primary melanocytic lesion.
Birinyi, Paul +6 more
core +3 more sources
Malignant melanoma accounts for about 1–3% of all malignancies in the West, especially in the United States. More than 9000 people die each year. In general, it is difficult to characterize a skin lesion from a photograph.
Chan-Il Kim +4 more
doaj +1 more source
microRNA-33a-5p increases radiosensitivity by inhibiting glycolysis in melanoma. [PDF]
Glycolysis was reported to have a positive correlation with radioresistance. Our previous study found that the miR-33a functioned as a tumor suppressor in malignant melanoma by targeting hypoxia-inducible factor1-alpha (HIF-1α), a gene known to promote ...
Cao, Ke +12 more
core +1 more source
Malignant melanoma is one of the most common malignant diseases of the gastrointestinal tract. It has been reported that the malignant melanoma metastasizes not only to the small intestine due to the abundant blood supply, but also to the stomach, colon,
Jeong Seok Lee +7 more
doaj +1 more source
Metastatic malignant melanoma of the breast: report of a case and review of the literature [PDF]
Melanoma is the most rapidly increasing cancer in the world. Associated morbidity and mortality are mainly related to metastatic potential. Metastases to the breast from malignant melanoma are rare and represent only 1.3%–2.7% of reported cases.
Aikaterini Mastoraki +6 more
doaj +3 more sources
Understanding signaling cascades in melanoma [PDF]
Understanding regulatory pathways involved in melanoma development and progression has advanced significantly in recent years. It is now appreciated that melanoma is the result of complex changes in multiple signaling pathways that affect growth control,
Akslen L. A. +58 more
core +1 more source

