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Diagnostic and Therapeutic Challenges of Malignant Pleural Mesothelioma [PDF]

open access: yesDiagnostics, 2022
Malignant pleural mesothelioma is a rare cancer characterized by a very poor prognosis. Exposure to asbestos is the leading cause of malignant pleural mesothelioma.
Jacopo Moro   +13 more
doaj   +2 more sources

Insulin-Like Growth Factor 2 mRNA Binding Protein 3 Promotes Cell Proliferation of Malignant Mesothelioma Cells by Downregulating p27Kip1

open access: yesFrontiers in Oncology, 2022
Malignant mesothelioma is a tumor with a poor prognosis, mainly caused by asbestos exposure and with no adequate treatment yet. To develop future therapeutic targets, we analyzed the microarray dataset GSE 29370 of malignant mesothelioma and reactive ...
Ihiro Endo   +6 more
doaj   +1 more source

Concomitant Nephrotic Syndrome and Cryoglobulinemia in a Case of Malignant Mesothelioma

open access: yesCase Reports in Nephrology, 2022
Malignant pleural mesothelioma is rarely associated with nephrotic syndrome. Cryoglobulinemia is found in various pathological statuses, such as hepatitis C virus infection but rarely in malignant neoplasms.
Kei Nagai   +3 more
doaj   +1 more source

Diagnostic utility of BRCA1-associated protein 1 (BAP1), Programmed Cell Death4 (PCD4) and Epithelial membrane antigen (EMA) expression in differentiation of malignant mesothelioma from reactive mesothelial cell hyperplasia in both cytology and cell block [PDF]

open access: yesZagazig University Medical Journal, 2022
Background: Malignant pleural mesothelioma (MPM) is the most lethal tumor arising from the mesothelial cells. Sometimes, it is difficult to be diagnosed based on morphology alone as reactive mesothelial hyperplasia (RMH) and some metastatic carcinomas ...
Hanaa Atwa   +2 more
doaj   +1 more source

Case report: Rare intrapulmonary malignant mesothelioma complicated with myositis

open access: yesFrontiers in Oncology, 2022
Malignant pleural mesothelioma is an uncommon aggressive tumor. Its incidence is even lower when the lung parenchyma is the primary site. Myositis is a common paraneoplastic syndrome, but it rarely presents with malignant pleural mesothelioma.
Dandan Gong, Jian Yu, Xiaodong Jiang
doaj   +1 more source

The role of CD24 as a potential biomarker for malignant pleural mesothelioma

open access: yesEgyptian Journal of Chest Disease and Tuberculosis, 2023
Objectives Pleural mesothelioma is a rapidly progressing pleural neoplasm caused by asbestos exposure of a long latency around 30-40 years. Patients with mesothelioma are usually diagnosed at a late stage with poor outcomes in terms of morbidity and ...
Mohamed Shaaban Mousa   +4 more
doaj   +1 more source

The Significance of BRCA-associated Protein (BAP1) and Calretinin Expression in Malignant Pleural Mesothelioma and Non-small Cell Lung Carcinoma: An Immunohistochemical Study [PDF]

open access: yesZagazig University Medical Journal, 2019
Background: Malignant pleural mesothelioma (MPM) and non-small cell lung carcinoma (NSCLC) are common diseases with rising incidence, patients have different prognosis and are treated differently, and thus it is very important to diagnose these ...
Amira Salem   +3 more
doaj   +1 more source

Malignant Peritoneal Mesothelioma With EWSR1-ATF1 Fusion: A Case Report

open access: yesJTO Clinical and Research Reports, 2021
Malignant mesothelioma with EWSR1-ATF1 fusion is a rare malignancy described in young adults without asbestos exposure. To the best of our knowledge, outcomes to local and systemic therapies for this subtype of malignant mesothelioma have not been ...
Helen Ke, MBBS (Hons)   +8 more
doaj   +1 more source

Can BAP1 expression loss in mesothelial cells be an indicator of malignancy? [PDF]

open access: yesJournal of Pathology and Translational Medicine, 2020
Background Malignant mesothelioma is a highly aggressive tumor that can be confused with a benign mesothelial lesion, especially cytomorphologic lesions. BRCA1-associated protein 1 (BAP1) acts as a tumor suppressor.
Hanife Gulnihal Ozdemir   +2 more
doaj   +1 more source

Highlighting the immunohistochemical differences of malignant mesothelioma subtypes via case presentations

open access: yesThoracic Cancer, 2023
Malignant mesothelioma (MM) is a rare tumor of mesothelial cells, with an increasing incidence both in developed and developing countries. MM has three major histological subtypes, in order of frequency, according to the World Health Organization (WHO ...
Anita Sejben   +5 more
doaj   +1 more source

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