Results 121 to 130 of about 1,884,278 (256)

Screening of malignant neoplasms in the population of the Republic of Sakha (Yakutia)

Якутский медицинский журнал
This article describes the incidence of malignant neoplasms in the Sakha Republic’s population selected for screening studies and presents an assessment of the results of the Onkopoisk. Sakha (mass screening tests) pilot project. Screening is carried out
L. N. Afanasyeva, T. M. Klimova, O. Yu. Aleksandrova, L. M. Kogonia, T. I. Nikolaeva, T. E. Belolyubskaya, F. G. Ivanova, P. V. Nikiforov, V. N. Leznev, M. I. Tikhinova   +9 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Malignant neoplasms and sexual and gender minorities: Scoping Review

Mapping the scientific evidence on malignant neoplasms and sexual and gender minorities: a scoping ...
Deborah Franscielle da Fonseca, Patrícia Peres de Oliveira, Janaína Sandra Pereira   +2 more
core   +1 more source

Analysis of the structure of deaths from sporadic metachronous primary multiple malignant neoplasms in a general hospital

Бюллетень сибирской медицины
Aim. To analyze the structure of deaths from sporadic metachronous primary multiple malignant neoplasms in 2017–2023 in a multidisciplinary inpatient facility.Materials and methods.
M. V. Zavyalova, A. V. Zavyalov, D. S. Pismenny, L. V. Pikalova, L. D. Zhuykova, Yu. M. Zhuykova, M. Yu. Grishchenko, S. V. Vtorushin, N. V. Litvyakov, M. V. Perelmuter   +9 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Malignant mesenchymal neoplasms of the oromaxillofacial area. The diagnostic problems

, 1993
Oral and maxillo-facial mesenchymal malignant neoplasms are rare. They involve nosologic, diagnostic and therapeutic problems. Clinical cases of soft and bone tissue are reported.
TARTARO, Gianpaolo, COLELLA, Giuseppe, TARTARO S, FAILLACE G, ROSSIELLO, Raffaele   +4 more
core  

MALIGNANT NEOPLASMS IN CHILDREN: CLINICAL MANIFESTATIONS AND DIAGNOSIS

, 2017
Treatment efficacy for children with cancer depends on the diagnosis timeliness since the earlier expert care has been started, the higher likelihood there is to achieve remission.
Dmitrij D. Sevryukov, Alisa S. Vilkova, Maxim Yu. Rykov   +2 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Primary Non-Hodgkin's Malignant Lymphoma of the Sinonasal Tract [PDF]

, 2009
Primary non-Hodgkin’s lymphomas (NHL) of the sinonasal tract are rather uncommon entities. Morphologically and radiographically, sinonasal lymphomas are difficult to distinguish from other malignant neoplasms or non- neoplastic processes.
Gupta, Nitin, Bhagat, Sanjeev, Varshney, Saurabh, Singh, Rakesh Kumar, Bist, SS   +4 more
core