Results 101 to 110 of about 1,520,254 (297)

Perforated small intestine in a patient with T-cell lymphoma; a rare cause of peritonitis [PDF]

open access: yes, 2016
The nontraumatic perforations of the small intestine are pathological entities with particular aspects in respect to diagnosis and treatment. These peculiarities derive from the nonspecific clinical expression of the peritonitis syndrome, and from the ...
Banu, Petrisor   +3 more
core   +3 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Hypothesis of the basic biological sense of cancer revisited: a putative explanation of Peto's paradox [PDF]

open access: yes, 2017
The conventional interpretation of cancer, summarized in the unified genetic theory of carcinogenesis, assumes that the malignant cell is the anatomical and physiological unit of cancer.
Bustuoabad, Oscar David   +1 more
core  

Studies on the clinical significance of nonesterified and total cholesterol in urine [PDF]

open access: yes, 1981
Gas-liquid chromatographic determinations of nonesterified and total urinary cholesterol were performed in 137 normals, 264 patients with various internal diseases without evidence of neoplasias or diseases of the kidney or urinary tract, 497 patients ...
A. Pickel   +35 more
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

CHANGES OF DENTAL STATUS IN PATIENTS WITH MALIGNANT TUMOR OF OROPHARYNGEAL REGION DURING ANTITUMOR TREATMENT

open access: yesКубанский научный медицинский вестник, 2017
Aim. A review of the literature on the effect of the antitumor treatment on the dental status of patients with malignant neoplasms of the oropharyngeal region.Materials and methods.
E. V. IZHNINA   +2 more
doaj   +1 more source

Metachronous Intraductal Papillary Neoplasm of the Bile Duct and Intraductal Papillary Mucinous Neoplasm of the Pancreas in a Patient Diagnosed With Mucinous Adenocarcinoma. [PDF]

open access: yes, 2019
Intraductal papillary neoplasm of the bile duct (IPNB) is a rare biliary tumor, which shares some radiologic and histologic similarities with pancreatic intraductal papillary mucinous neoplasm (IPMN).
Brennan, Gregory T, Lee, John G
core   +1 more source

Immunosuppression and Malignant Neoplasms [PDF]

open access: yesNew England Journal of Medicine, 1970
T E, Starzl, I, Penn, C G, Halgrimson
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Histopathological Features of Nevus Sebaceous and Superimposed Skin Tumors

open access: yesJournal of Skin Cancer
Conclusion: Our study revealed that malignant tumors were more common than benign lesions in patients with NS. Benign neoplasms were more frequent in women. Malignant neoplasms were detected in patients aged more than 25 years.
Paridokht Karimian   +5 more
doaj   +1 more source

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