Results 81 to 90 of about 1,884,278 (256)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

CHANGES OF DENTAL STATUS IN PATIENTS WITH MALIGNANT TUMOR OF OROPHARYNGEAL REGION DURING ANTITUMOR TREATMENT

Кубанский научный медицинский вестник, 2017
Aim. A review of the literature on the effect of the antitumor treatment on the dental status of patients with malignant neoplasms of the oropharyngeal region.Materials and methods.
E. V. IZHNINA, E. V. KOCHUROVA, K. G. SEFERYAN   +2 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Multiple primary malignant neoplasms associated with genitourinary cancer [PDF]

, 1996
当院泌尿器科で発見された尿路性器癌392例の中, 重複癌(三重癌も含む)と診断された42例について臨床的検討を行った. 1)発生頻度は重複癌9.9%, 三重癌0.7%であった.男女比は5:1であった. 2)尿路性器系重複癌の臓器別発生頻度は単発癌のそれとほぼ同じであったが, 前立腺癌にやや多い傾向がみられた. 3)他臓器系の癌の組み合わせでは, 胃癌, 膵癌など消化器系の癌の比率が高い傾向がみられた.
深貝, 隆志, 石原, 理裕, 丸山, 邦夫, 内藤, 善文, 船橋, 健二郎   +4 more
core  

Histopathological Features of Nevus Sebaceous and Superimposed Skin Tumors

Journal of Skin Cancer
Conclusion: Our study revealed that malignant tumors were more common than benign lesions in patients with NS. Benign neoplasms were more frequent in women. Malignant neoplasms were detected in patients aged more than 25 years.
Paridokht Karimian, Naz Zargar Javaheri, Kaveh Gharaei Nejad, Hojat Eftekhari, Elahe Rafiei, Rana Rafiei   +5 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

EPIDEMIOLOGY OF MALIGNANT NEOPLASMS OF ORAL CAVITY IN GREECE

, 1992
THIS STUDY DEALS WITH THE INCIDENCE AND MORTALITY MALIGNANT NEOPLASMS OF ORAL CAVITY AND PHARYNX, ACCORDING TO DATA PROVIDED BY THE NATIONAL STATISTICAL SERVICE OF GREECE.
Κωνσταντινίδης, Ρήγας
core   +1 more source

Endoscopic Ultrasound Fine-Needle Aspiration Characteristics of Primary Adenocarcinoma versus Other Malignant Neoplasms of The Pancreas

Canadian Journal of Gastroenterology, 2012
BACKGROUND: Endoscopic ultrasound (EUS) with fine-needle aspiration (FNA) is often used to assist in the evaluation of pancreatic lesions and may help to diagnose benign versus malignant neoplasms.
Veronika Gagovic, Bret J Spier, Ryan J DeLee, Courtney Barancin, Mary Lindstrom, Michael Einstein, Siobhan Byrne, Josephine Harter, Rashmi Agni, Patrick R Pfau, Terrence J Frick, Anurag Soni, Deepak V Gopal   +12 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source