Results 61 to 70 of about 1,520,254 (297)

Malignant neoplasms in the aged.

open access: yesNippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics, 1987
高齢者の悪性腫瘍は一般に進行の緩かな場合が多いが, その治療面では困難を伴うことが多くその対策は十分とはいえない. 即ち若年では強固な宿主の故に治療も十分に行うことが出来, 従って進行癌でも完全寛解が比較的容易にもたらされ治癒せしめうることもある. 一方高齢者では宿主の抵抗力が減退し十分な化学療法を行うことが出来ず, 経過は長いとはいえ完全寛解又は治癒を期待することは難しい. 何れにしても宿主の老化を防ぎ, 抵抗力乃至免疫能を上げることが必要となって来る.免疫能の低下した状態にある癌の宿主は化学療法を行うことにより更に低下を来すので, 免疫賦活療法は必要であるが, 特に完全寛解後には再発防止の意味から重要である. 更にこの処置は次に問題となるであろう2次癌, 3次癌の予防にも関係して来ることになる.
openaire   +3 more sources

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Cancer mortality in Portugal [PDF]

open access: yes, 2018
Following Population News, Trends and Attitudes #6 it was possible to identify that, despite circulatory system diseases represent the leading causes of death (COD) in Portugal, the share of deaths caused by neoplasms is increasing with time.
Ribeiro, Filipe
core  

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Primary Non-Hodgkin's Malignant Lymphoma of the Sinonasal Tract [PDF]

open access: yes, 2009
Primary non-Hodgkin’s lymphomas (NHL) of the sinonasal tract are rather uncommon entities. Morphologically and radiographically, sinonasal lymphomas are difficult to distinguish from other malignant neoplasms or non- neoplastic processes.
Bhagat, Sanjeev   +4 more
core  

Solid-pseudopapillary tumor of the pancreas: A single center experience [PDF]

open access: yes, 2016
open6noAim of this study was to review the institutional experience of solid-pseudopapillary tumors of the pancreas with particular attention to the problems of preoperative diagnosis and treatment.
Alberto Fantin   +5 more
core   +3 more sources

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

Malignant neoplasms ozone therapy

open access: yesRUDN Journal of Medicine
The development of effective therapeutic approaches for the treatment of malignant neoplasms is one of the priorities of modern biomedical research. Disappointing data from epidemiological indicators and statistical calculations of morbidity dictate the ...
Pavel Yu. Andreev   +6 more
doaj   +1 more source

Role of Fine Needle Aspiration Cytology in Salivary Gland Pathology and its Histopathological Correlation: A Two Year Prospective Study in Western India. [PDF]

open access: yes, 2012
Background and objectives: Salivary gland lesions account for 2-6.5% of all the neoplasms of the head and neck. Fine needle aspiration cytology (FNAC) is being increasingly used in the diagnosis of salivary gland lesions.
Agravat, AH   +3 more
core   +1 more source

Some considerations on the WHO Histological classification of laryngeal neoplasms [PDF]

open access: yes, 2019
A new edition of the World Health Organization (WHO) Histological classification of tumours of the hypopharynx, larynx, trachea and parapharyngeal space was published in 2017.
Devaney, Kenneth O.   +3 more
core   +2 more sources

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