Results 51 to 60 of about 1,884,278 (256)
Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz +12 more
wiley +1 more source
Malignant neoplasms ozone therapy
The development of effective therapeutic approaches for the treatment of malignant neoplasms is one of the priorities of modern biomedical research. Disappointing data from epidemiological indicators and statistical calculations of morbidity dictate the ...
Pavel Yu. Andreev +6 more
doaj +1 more source
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani +7 more
wiley +1 more source
Predisposing Factors and Clinico-Pathological Presentation of Malignant Lesions of the Oro-Facial Region Among Patients Attending the Muhimbili National Hospital in Dar-es-Salaam, Tanzania [PDF]
The oro-facial region is made up of a complex anatomical relationship of structures of which may be a source of development of malignant lesions. Often, patients present at the oral and maxillofacial unit of Muhimbili National Hospital with a variety of ...
Berege, Gemma Z
core
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk +10 more
wiley +1 more source
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
Cumulative incidence of second malignant neoplasms.
Cumulative incidence of second malignant neoplasms.
Hee Young Ju (5979278) +6 more
core +1 more source
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann +8 more
wiley +1 more source
Objective This study aimed to investigate the usefulness of endoscopic ultrasound‐guided tissue acquisition (EUS‐TA) for diagnosing focal liver lesions in patients with a history of multiple primary malignant neoplasms.
Yuichi Takano +9 more
doaj +1 more source
Background: The management of musculoskeletal neoplasms requires an accurate diagnosis, histologic type, and degree of tumor differentiation. Aim: The present study was undertaken to compare the accuracy of fine-needle aspiration cytology (FNAC) and ...
Ivreet Kaur +4 more
doaj +1 more source

