Results 101 to 110 of about 1,853,921 (224)

Role of FOXR2 in malignant peripheral nerve sheath tumor progression [PDF]

, 2013
This research was supported by the Undergraduate Research Opportunities Program (UROP).Otto, George. (2013). Role of FOXR2 in malignant peripheral nerve sheath tumor progression.
Otto, George
core  

DNA Hypomethylation Is Not Cell Intrinsically Toxic to Polycomb Repressive Complex 2 Deficient Malignant Peripheral Nerve Sheath Tumors

Genes, Chromosomes and Cancer, Volume 65, Issue 8, August 2026.
ABSTRACT Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft tissue sarcomas and the most common cause of disease‐associated death for neurofibromatosis type 1 (NF1) patients. In the context of NF1, MPNSTs develop from benign premalignant precursors and the transition to malignancy is typically accompanied by loss of the polycomb ...
Madilyn R. Stahl, Christopher M. Stehn, Zachary J. Seeman, Christopher Faulk, David A. Largaespada   +4 more
wiley   +1 more source

Perineural extension of cutaneous desmoplastic melanoma mimicking an intracranial malignant peripheral nerve sheath tumor [PDF]

, 2011
The authors present a case illustrating the importance of obtaining a biopsy of any facial skin lesions in a patient presenting with an intracranial tumor involving the facial or trigeminal nerve. Conventional malignant melanoma metastasizes to the brain
Bruce Mickey, Kimmo J. Hatanpaa, Michael J. Wells, Samuel L. Barnett   +3 more
core   +1 more source

Prognostic Value of Cranial Nerve Invasion in T4‐Stage Nasopharyngeal Carcinoma: A Retrospective Cohort Study With a Median Follow‐Up of 136 Months

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background The objective of this study was to evaluate the prognostic value of cranial nerve invasion (CNI) in T4‐stage nasopharyngeal carcinoma (NPC) patients with nonmetastatic. Methods We retrospectively analyzed 299 T4‐stage NPC patients with nonmetastatic disease in the Cancer Hospital of Shantou University Medical College.
Cuidai Zhang, Hui Liu, Xuejia Liu, Yihao Ye, Zeman Cai, Zewei Chen, Qizhi Zheng   +6 more
wiley   +1 more source

Malignant Peripheral Nerve Sheath Tumour of the Maxilla [PDF]

, 2014
A 38-year-old man was diagnosed with malignant peripheral nerve sheath tumour of the maxilla. He was treated with total maxillectomy. Histopathological examination of the resected specimen revealed a close resection margin.
Sameer Bakhshi, Puja Sahai, Bidhu Kalyan Mohanti, Suman Bhasker, Devajit Nath, Chirom Amit Singh, Subhash Chander   +6 more
core   +1 more source

NF1 Leucine Rich Domain‐Derived Extracellular Vesicles Remodel the Glioblastoma Immune Microenvironment via an ADAM17‐Associated Inflammatory Program

Journal of Extracellular Vesicles, Volume 15, Issue 8, August 2026.
NF1‐LRD‐derived EVs suppress glioma cells' invasion and reprogram TAMs through the ADAM17‐TNFα‐ICAM‐1 signaling axis. These EVs reduce migration recruitment, enhance pro‐inflammatory polarization, and modulate key pathways, collectively reshaping the GBM TME. (Created with Biorender.com) ABSTRACT Extracellular vesicles (EVs) are increasingly recognized
Yuganthini Vijayanathan, Jacqueline YT Yeo, Janice HY Tan, Fikri Bin Mohamed, Bernett Lee, Tatsuya Kozaki, Nurashikin Abdul Halim, Rachel LY Ho, Hai Tao Tu, Zhi Wei Zhang, Jann N. Sarkaria, Li Zeng, Florent Ginhoux, Ivy AW Ho   +13 more
wiley   +1 more source

Malignant Peripheral Nerve Sheath Tumors in Childhood [PDF]

, 2012
Purpose: We aimed to review clinical characteristics, treatment results, and outcome for pediatric patients with malignant peripheral nerve sheath tumors (MPNSTs)
Ali Varan, Demir, Haci Ahmet, AKYÜZ, CANAN, Tezer Kutluk, Münevver Büyükpamukçu, Hac Ahmet Demir, YALÇIN, BİLGEHAN, VARAN, ALİ, Bilgehan Yalçn, Kutluk, Tezer, Canan Akyüz, BÜYÜKPAMUKÇU, MÜNEVVER   +11 more
core   +1 more source

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, Volume 7, Issue 4, August 2026.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source

Long‐Term Local Control and Mortality After Transpupillary Thermotherapy of Small Uveal Melanomas

Clinical &Experimental Ophthalmology, Volume 54, Issue 6, Page 832-844, August 2026.
ABSTRACT Background Transpupillary thermotherapy (TTT) is used for selected small choroidal melanocytic tumours, either as primary treatment or as an adjunct to plaque brachytherapy. We compared long‐term local recurrence and mortality outcomes after primary TTT alone, plaque brachytherapy combined with TTT (brachy+TTT), and plaque brachytherapy alone (
Maria Fili, Malin Ermedahl Conradi, Maya Klaff Dahl, Shiva Sabazade, Manuel Casselholm De Salles, Gustav Stålhammar   +5 more
wiley   +1 more source

Benign and Malignant Peripheral Nerve Sheath Tumors of the Oral Cavity: Two-Case Series Emphasizing Diagnostic Challenges

Diagnostics
Background: Peripheral nerve sheath tumors of the oral cavity are rare and encompass both benign and malignant entities. Differentiating between these lesions remains challenging due to overlapping clinical and histopathological characteristics.
Evgeniy Aleksiev, Dimitar Kosturkov, Tihomir Dikov, Vesela Ivanova, Zornitsa Mihaylova   +4 more
doaj   +1 more source