Results 1 to 10 of about 25,703 (229)

Human cutaneous neurofibroma matrisome revealed by single-cell RNA sequencing

open access: yesActa Neuropathologica Communications, 2021
Neurofibromatosis Type I (NF1) is a neurocutaneous genetic syndrome characterized by a wide spectrum of clinical presentations, including benign peripheral nerve sheath tumor called neurofibroma.
Jean-Philippe Brosseau   +6 more
doaj   +2 more sources

Histopathological Variants of Cutaneous Neurofibroma: A Compendious Review

open access: yesDermatopathology, 2022
The first description of histopathological variants of neurofibroma dates back to 1994. Over the years, many individual case reports elucidating unusual histologic features in neurofibroma have been added to the literature, some of which have defined ...
Neha S. Nagrani, Jag Bhawan
doaj   +2 more sources

Neurofibroma Development in Neurofibromatosis Type 1: Insights from Cellular Origin and Schwann Cell Lineage Development

open access: yesCancers, 2022
Simple Summary Neurofibromas have been thought to originate from cells within the Schwann cell lineage, while no consensus has been reached so far about the specific time of initiation and the exact cellular origin.
Zhichao Wang, Wang Zhi-Chao
exaly   +2 more sources

Imaging diagnosis of plexiform neurofibroma- unravelling the confounding features: A report of two cases

open access: yesRadiology Case Reports, 2021
Peripheral nerve sheath tumors such as neurofibroma, comprise 5% of all benign soft tissue tumors and usually occur due to an underlying neurofibromatosis.
Dr. Shabnam Bhandari Grover, MD, DNBE, FICR, MNAMS, MRCR, FICMU   +4 more
doaj   +2 more sources

Neurofibroma of the Palate [PDF]

open access: yesCase Reports in Dentistry, 2014
Neurofibroma is a benign peripheral nerve sheath tumor comprising variable mixture of Schwann cells, perineurial-like cells, and fibroblasts. Neurofibroma may occur as solitary lesion or as part of a generalised syndrome of neurofibromatosis or very ...
Tirumalasetty Sreenivasa Bharath   +5 more
doaj   +3 more sources

Neurofibroma of the Lingual Nerve: A Case Report

open access: yesKaohsiung Journal of Medical Sciences, 2006
A neurofibroma of the lingual nerve is a rare clinical finding, the most common lesion site of a lingual neurofibroma being the tongue. In most situations, it is difficult to determine the precise nerve origins.
Hsun-Mo Wang   +4 more
exaly   +3 more sources

Proof-of-principle of NF1 gene therapy in plexiform neurofibroma xenograft mouse models [PDF]

open access: yesCommunications Biology
Neurofibromatosis type I is a rare neurocutaneous syndrome characterized by the development of disfiguring neurofibroma tumors with unmet clinical needs.
Dhanushka Hewa Bostanthirige   +11 more
doaj   +2 more sources

Plexiform Neurofibroma

open access: yesCleveland Clinic Journal of Medicine, 2016
Plexiform neurofibromas represent an uncommon variant (30%) of neurofibromatosis type 1 (NF-1) in which neurofibromas arise from multiple nerves as bulging and deforming masses involving also connective tissue and skin folds.We report a rare case of a 30-
G. Tchernev   +5 more
semanticscholar   +3 more sources

Neurofibroma of the Colon: A Diagnostic Mimicker of Gastrointestinal Stromal Tumor

open access: yesCase Reports in Gastroenterology, 2016
Gastrointestinal neurofibroma usually develops as diffuse gastrointestinal involvement in neurofibromatosis type 1 patients. Only 4 cases of sporadic colonic neurofibroma in a patient without neurofibromatosis type 1 have been reported in the English ...
Soomin Ahn   +2 more
doaj   +2 more sources

Basement membrane proteins in extracellular matrix characterize NF1 neurofibroma development and response to MEK inhibitor

open access: yesJournal of Clinical Investigation, 2023
Neurofibromatosis type 1 (NF1) is one of the most common tumor-predisposing genetic disorders. Neurofibromas are NF1-associated benign tumors. A hallmark feature of neurofibromas is an abundant collagen-rich extracellular matrix (ECM) that constitutes ...
Chunhui Jiang   +7 more
semanticscholar   +1 more source

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