Results 41 to 50 of about 25,703 (229)
Cancer Discovery, 2018 Neurofibromatosis type 1 (NF1) is a cancer predisposition disorder that results from inactivation of the tumor-suppressor Neurofibromin, a negative regulator of RAS signaling.
Zhiguo Chen +11 more
semanticscholar +1 more source
Isolated Plexiform Neurofibroma of Arm with Unusual Presentation - A Rare Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2015 Plexiform neurofibroma (PNF) arises as a diffuse mass from nerve trunk and leads to overgrowth of cutis and subcutis structure. This is a case report of 20-year-old male, presented to our hospital with a giant ulcerated swelling over his left arm ...
PANKAJ KUMAR MISHRA +3 more
doaj +1 more source
New insights into the neurofibroma tumor cells of origin
Neuro-Oncology Advances, 2019 Neurofibromatosis type I (NF1) is a debilitating inherited tumor syndrome affecting around 1 in 3000 people. Patients present with a variety of tumors caused by biallelic loss of the tumor suppressor neurofibromin (NF1), a negative regulator of Ras ...
Stephen Li, Zhiguo Chen, L. Le
semanticscholar +1 more source
Developmental Dynamics, EarlyView.Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley +1 more source
Unusual Case of a Proptosed Eye: Isolated Right Maxillary Neurofibroma
Case Reports in Pathology, 2016 Neurofibroma is a slow growing benign tumour of the peripheral nerve sheath which is frequently associated with neurofibromatosis type 1 (Prakash et al., 2014).
Darren Yap +2 more
doaj +1 more source
Solitary neurofibroma of the heart
Journal of International Medical Research, 2020 Solitary neurofibroma of the heart is extremely unusual. Few reports of neurofibroma in the left ventricle have been published. In this case report, we present the results of transthoracic echocardiography, myocardial contrast echocardiography, cardiac ...
Pei Jing Li +7 more
doaj +1 more source
Case report: Primary intraosseous neurofibroma of maxilla
Journal of Dr. NTR University of Health Sciences, 2020 The present article is a case report of solitary neurofibroma of oral cavity in a 50-year-old male patient. Patient reported with chief complaint of swelling in relation to upper front teeth region since 2 months.
Y Raghavendra Reddy +3 more
doaj +1 more source
BMC Oral Health, 2019 Neurofibromas (NF) are benign tumors of the peripheral nerves that are composed of Schwann cells, perineural-like cells and fibroblasts. The differential diagnosis for a solitary intraneural variant of neurofibroma arising in the floor of the mouth is ...
E. Broly +3 more
semanticscholar +1 more source
NF1 patient missense variants predict a role for ATM in modifying neurofibroma initiation
Acta Neuropathologica, 2019 In Neurofibromatosis type 1, NF1 gene mutations in Schwann cells (SC) drive benign plexiform neurofibroma (PNF), and no additional SC changes explain patient-to-patient variability in tumor number.
Yanan Yu +13 more
semanticscholar +1 more source
Head &Neck, EarlyView.ABSTRACT Objectives To identify longitudinal swallowing‐related QoL trajectories after carotid body tumor (CBT) resection and explore associated characteristics. Methods A prospective study assessed swallowing‐related QoL using the MD Anderson Dysphagia Inventory at nine timepoints from preoperation to 12 months postdischarge.
Pan Chen +8 more
wiley +1 more source