Results 51 to 60 of about 25,703 (229)

STAT3 inhibition reduces macrophage number and tumor growth in neurofibroma

open access: yesOncogene, 2018
Plexiform neurofibroma, a benign peripheral nerve tumor, is associated with the biallelic loss of function of the NF1 tumor suppressor in Schwann cells.
Jonathan S. Fletcher   +8 more
semanticscholar   +1 more source

Nail Toxicities Associated With Anticancer Therapies in Children

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Nail toxicities are a frequent yet often underrecognized component of dermatologic adverse events in children receiving anticancer therapies. Both conventional cytotoxic chemotherapy and newer targeted agents can affect the nail matrix, nail bed and periungual tissues, producing a broad spectrum of clinical manifestations that range from ...
Luca Rapparini, Michela Starace
wiley   +1 more source

Primary Bladder Neurofibroma: A Rare Case with Clinical Implications and Diagnostic Challenges [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2015
Neurofibroma of the genito-urinary tract is rare. Urinary bladder is the commonest organ involved in cases of urinary tract involvement. Patients present early in life and there is male preponderance.
Srikanth Umakanthan   +4 more
doaj   +1 more source

Robust surgical approach for cutaneous neurofibroma in neurofibromatosis type 1.

open access: yesJCI Insight, 2019
BACKGROUND Cutaneous neurofibromas (cNF) are physically disfiguring, painful, and cause extensive psychologic harm in patients with neurofibromatosis type 1 (NF1). There is currently no effective medical treatment and surgical procedures are inaccessible
B. Chamseddin   +4 more
semanticscholar   +1 more source

Transoral Robotic Resection of Glossopharyngeal Neurofibroma: A Case Report

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT This case highlights the diagnostic challenges posed by rare oropharyngeal neurofibromas, their potential to mimic other conditions, and the novel application of transoral robotic surgery (TORS) for the management of an oropharyngeal neurofibroma. A 47‐year‐old female presented with a 1‐year history of a left tonsillar mass.
Cody L. Messick   +7 more
wiley   +1 more source

Benign Cutaneous Peripheral Nerve Sheath Tumor with Hybrid Features: Report of Two Cases with Schwannoma/Perineurioma and Schwannoma/Neurofibroma Components

open access: yesDermatopathology, 2017
Hybrid benign peripheral nerve sheath tumors are rare tumors exhibiting areas of more than one neural neoplasm such as schwannoma/neurofibroma, neurofibroma/perineurioma, or schwannoma/perineurioma.
Shirien Shanouda, Gürkan Kaya
doaj   +1 more source

Association of plexiform neurofibroma volume changes and development of clinical morbidities in neurofibromatosis 1

open access: yesNeuro-Oncology, 2018
Background Plexiform neurofibromas (PN) in neurofibromatosis 1 (NF1) can cause substantial morbidities. Clinical trials targeting PN have recently described decreases in PN volumes.
A. Gross   +9 more
semanticscholar   +1 more source

Plexiform neurofibroma of the submandibular gland in patient with von Recklinghausen's disease

open access: yesRare Tumors, 2011
Plexiform neurofibroma of the submandibular gland is an extremely rare tumor. Herein, we report a case of plexiform neurofibroma in a patient with a von Recklinghausen's disease (NF-1) who presented with a submandibular mass mimicking a submandibular ...
Hassan Al Bisher   +3 more
doaj   +1 more source

Arteriovenous malformation underlying a plexiform neurofibroma: An unusual presentation

open access: yesIndian Dermatology Online Journal, 2017
Vascular abnormalities associated with neurofibromatosis type 1 are well described in the literature, however, arteriovenous malformation is a very rare finding in neurofibromatosis type 1.
Zaheer Abbas, Sepideh Khani, Javad Zare
doaj   +1 more source

An inflammatory gene signature distinguishes neurofibroma Schwann cells and macrophages from cells in the normal peripheral nervous system

open access: yesScientific Reports, 2017
Neurofibromas are benign peripheral nerve tumors driven by NF1 loss in Schwann cells (SCs). Macrophages are abundant in neurofibromas, and macrophage targeted interventions may have therapeutic potential in these tumors. We generated gene expression data
Kwangmin Choi   +6 more
semanticscholar   +1 more source

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