Results 51 to 60 of about 14,742 (226)
Primary Bladder Neurofibroma: A Rare Case with Clinical Implications and Diagnostic Challenges [PDF]
Journal of Clinical and Diagnostic Research, 2015 Neurofibroma of the genito-urinary tract is rare. Urinary bladder is the commonest organ involved in cases of urinary tract involvement. Patients present early in life and there is male preponderance.
Srikanth Umakanthan +4 more
doaj +1 more source
Solitary neurofibroma in patients without neurofibromatosis: biological and clinical aspects [PDF]
, 2008 El neurofibroma es uno de los tumores de la vaina neural que se da por una proliferación de células de Schwann, mastocitos, fibroblastos y mayor producción de colágeno, es generalmente benigno y puede ser una manifestación de neurofibromatosis.
Flórez Salamanca, Ludwing +1 more
core
Intratumoral fat in neurofibroma
, 2002 Three cases of a solitary neurofibroma showing focal fatty changes are reported. Fatty changes in a neurofibroma are rarely observed and have not been reported, and also, the pathogenesis of neurofibroma has not been clarified.
이승헌
core +1 more source
Targeting KRAS for cancer therapy
British Journal of Pharmacology, EarlyView.In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia +4 more
wiley +1 more source
Neurofibroma cutáneo versus neurofibroma mixoide. reorientación diagnóstica a propósito de un caso clínico. [PDF]
, 2013 El neurofibroma es una proliferación neural benigna que se presenta con mayor frecuencia en la piel, es originada de los nervios periféricos conformados por células de Schwann y fibroblastos, donde los axones del nervio se entremezclan con el tumor.
Pinzón Jimenez, Darly Geraldine +9 more
core
Dermatopathology, 2017 Hybrid benign peripheral nerve sheath tumors are rare tumors exhibiting areas of more than one neural neoplasm such as schwannoma/neurofibroma, neurofibroma/perineurioma, or schwannoma/perineurioma.
Shirien Shanouda, Gürkan Kaya
doaj +1 more source
Clinical Genetics, EarlyView.Noonan syndrome and related conditions are caused by variants in multiple genes. We analyzed 456 Russian patients using a 23‐gene panel and found disease‐causing variants in non‐PTPN11 genes in 85 cases. NF1, SOS1, BRAF, and SHOC2 explained half of these diagnoses.
Anna Orlova +5 more
wiley +1 more source
International Journal of Dermatology, EarlyView.This review provides an update on the epidemiology, pathogenesis, and clinical/histologic features of cutaneous leiomyosarcoma. Prognostic factors (e.g., depth of tumor involvement, grade, etc.) that can facilitate risk stratification are also discussed, as are treatment approaches for this rare malignancy.
Tejas P. Joshi +4 more
wiley +1 more source
Arteriovenous malformation underlying a plexiform neurofibroma: An unusual presentation
Indian Dermatology Online Journal, 2017 Vascular abnormalities associated with neurofibromatosis type 1 are well described in the literature, however, arteriovenous malformation is a very rare finding in neurofibromatosis type 1.
Zaheer Abbas, Sepideh Khani, Javad Zare
doaj +1 more source
Selumetinib as a Target Therapy in Progressive Paediatric Low‐Grade Gliomas—Case Series (pLGG)
Journal of Paediatrics and Child Health, EarlyView.ABSTRACT Background Optic pathway gliomas (OPGs) occur in 15%–20% of children with neurofibromatosis type 1 (NF1). While smaller gliomas may be only monitored, the current standard of care for symptomatic ones relies on chemotherapy, most commonly carboplatin and vincristine.
Laura Trapani +12 more
wiley +1 more source