Results 121 to 130 of about 134,090 (261)

Long‐term outcome in a dog with a unilateral ovarian granulosa cell tumour with a concurrent non‐neoplastic abdominal effusion following ovariohysterectomy

open access: yesVeterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract An 8‐year‐old, entire, female Boston terrier presented with chronic abdominal distention and acute anorexia. Physical examination identified a palpable abdominal mass and ascites. Results of haematological and serum biochemical investigations were within reference range.
Toshiyuki Tanaka   +2 more
wiley   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

open access: yesInternational Journal of Cancer, Volume 158, Issue 2, Page 382-408, 15 January 2026.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner   +7 more
wiley   +1 more source

tRNA‐Derived Fragment tRF‐22 Promotes Immunosuppression by Inhibiting HnRNPAB Ubiquitination in Esophageal Squamous Cell Carcinoma

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
tRF‐22 fosters an immunosuppressive and pro‐oncogenic tumor microenvironment in ESCC by stabilizing hnRNPAB against TRIM25‐mediated ubiquitination and enhancing TGFβ2 expression, which increases PMN‐MDSCs infiltration and suppresses CD8+ T cells. Targeting tRF‐22 or blocking TGFβ signalling improves anti‐PD1 response, offering a promising therapeutic ...
Ling Pan   +10 more
wiley   +1 more source

Pigtail catheter as an alternative option for malignant pleural effusion other than pleurodesis: a case series

open access: yesPalliative Medicine in Practice
Patients with malignant pleural effusions should have pleural drainage as the preferred course of treatment. There are still issues in treating people who have malignant pleural effusions.
Yogendra Singhal   +3 more
doaj   +1 more source

CD30 as a Target Molecule in the Diagnosis and Therapy of Lymphomas

open access: yesAmerican Journal of Hematology, Volume 101, Issue 1, Page 110-128, January 2026.
ABSTRACT The tumor necrosis factor (TNF)‐receptor superfamily 8 receptor CD30 molecule is expressed in all tumor cells of Hodgkin lymphoma and anaplastic large cell lymphoma but is only weakly expressed in a small subset of large lymphoid cells in normal peripheral lymphoid tissues.
Harald Stein, Brunangelo Falini
wiley   +1 more source

Predictive Value of Serum Autotaxin for Hepatocellular Carcinoma Recurrence After Curative Radiofrequency Ablation

open access: yesCancer Medicine, Volume 15, Issue 1, January 2026.
Serum autotaxin (ATX) is a novel and robust biomarker for predicting hepatocellular carcinoma (HCC) recurrence after curative radiofrequency ablation (RFA). Elevated ATX levels independently predict recurrence, outperforming traditional markers and highlighting its potential for personalized post‐RFA surveillance strategies. ABSTRACT Background Despite
Takanobu Iwadare   +13 more
wiley   +1 more source

Clinical and Echocardiographic Insights Into Right Heart Masses: A Retrospective Study in China (2010–2023)

open access: yesCancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background This study aimed to analyze the clinical and echocardiographic characteristics, pathological profiles, and outcomes of right heart masses, and to explore the role of echocardiography in the evaluation of these masses. Methods We retrospectively analyzed 171 patients with echocardiographically diagnosed and pathologically confirmed ...
Lei Liu   +7 more
wiley   +1 more source

Pancreatic Pseudocyst With Thoracic Extension: A Clinicoradiological Case Report

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
CECT sagittal view shows an enlarged, heterogeneously enhancing pancreas with a peripancreatic collection extending into the posterior mediastinum and compressing the esophagus with massive right pleural fluid noted. ABSTRACT Pancreatic pseudocysts are encapsulated, enzyme‐rich peripancreatic fluid collections that typically develop following acute or ...
Sachchu Thapa   +7 more
wiley   +1 more source

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