Results 121 to 130 of about 134,090 (261)
Abstract An 8‐year‐old, entire, female Boston terrier presented with chronic abdominal distention and acute anorexia. Physical examination identified a palpable abdominal mass and ascites. Results of haematological and serum biochemical investigations were within reference range.
Toshiyuki Tanaka +2 more
wiley +1 more source
Therapeutic targeting of chromatin alterations in leukemia and solid tumors
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner +7 more
wiley +1 more source
tRF‐22 fosters an immunosuppressive and pro‐oncogenic tumor microenvironment in ESCC by stabilizing hnRNPAB against TRIM25‐mediated ubiquitination and enhancing TGFβ2 expression, which increases PMN‐MDSCs infiltration and suppresses CD8+ T cells. Targeting tRF‐22 or blocking TGFβ signalling improves anti‐PD1 response, offering a promising therapeutic ...
Ling Pan +10 more
wiley +1 more source
Patients with malignant pleural effusions should have pleural drainage as the preferred course of treatment. There are still issues in treating people who have malignant pleural effusions.
Yogendra Singhal +3 more
doaj +1 more source
CD30 as a Target Molecule in the Diagnosis and Therapy of Lymphomas
ABSTRACT The tumor necrosis factor (TNF)‐receptor superfamily 8 receptor CD30 molecule is expressed in all tumor cells of Hodgkin lymphoma and anaplastic large cell lymphoma but is only weakly expressed in a small subset of large lymphoid cells in normal peripheral lymphoid tissues.
Harald Stein, Brunangelo Falini
wiley +1 more source
S130 Preliminary data supporting a ‘direct to lat’ strategy in selected patients with suspected malignant pleural effusion [PDF]
Selina Tsim +4 more
openalex +1 more source
Serum autotaxin (ATX) is a novel and robust biomarker for predicting hepatocellular carcinoma (HCC) recurrence after curative radiofrequency ablation (RFA). Elevated ATX levels independently predict recurrence, outperforming traditional markers and highlighting its potential for personalized post‐RFA surveillance strategies. ABSTRACT Background Despite
Takanobu Iwadare +13 more
wiley +1 more source
ABSTRACT Background This study aimed to analyze the clinical and echocardiographic characteristics, pathological profiles, and outcomes of right heart masses, and to explore the role of echocardiography in the evaluation of these masses. Methods We retrospectively analyzed 171 patients with echocardiographically diagnosed and pathologically confirmed ...
Lei Liu +7 more
wiley +1 more source
Pancreatic Pseudocyst With Thoracic Extension: A Clinicoradiological Case Report
CECT sagittal view shows an enlarged, heterogeneously enhancing pancreas with a peripancreatic collection extending into the posterior mediastinum and compressing the esophagus with massive right pleural fluid noted. ABSTRACT Pancreatic pseudocysts are encapsulated, enzyme‐rich peripancreatic fluid collections that typically develop following acute or ...
Sachchu Thapa +7 more
wiley +1 more source

