Results 141 to 150 of about 134,090 (261)

Real‐World Outcomes With Low‐Dose Dasatinib (50 mg) in Imatinib‐Resistant Chronic Myeloid Leukemia in Chronic Phase: A Retrospective Analysis of Efficacy and Safety

Cancer Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background Dasatinib, a potent second‐generation tyrosine kinase inhibitor (TKI), is highly effective in chronic myeloid leukemia in chronic phase (CML‐CP) resistant to imatinib at standard dosing (100 mg daily), but is often limited by adverse events.
Nandhini Gangadaran, Harshal Mamlekar, Souvik Saha, Rajesh Kashyap, Sanjeev Yadav, Khaliqur Rahman, Ruchi Gupta, Mona Vijayaran, Manish Singh, Dinesh Chandra   +9 more
wiley   +1 more source

EGFR p.V774M/p. the S768I Compound Mutation in NSCLC Is a Good Prognostic Marker for IPHC‐ and Furmonertinib‐Based Treatment: A Case Report

Cancer Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background Intrapleural perfusion hyperthermic chemotherapy (IPHC) can be used to select specific lung cancer cells of a certain genotype. Some genetic mutations, especially epidermal growth factor receptor (EGFR) mutations, are potential markers for EGFR or other targeted therapies. Here, we report a unique case of a patient with EGFR p.V774M/
Yanan Wang, Guanying Ren, Zizheng Song, Ling Hu, Weiqi Li, Xiaolei Wang   +5 more
wiley   +1 more source

The value of computed tomography in discriminating malignant from non-malignant causes of unresolved unilateral pleural effusions: a systematic review [PDF]

, 2019
Simon Bertram Reuter, Therese Maria Henriette Naur, Paul Frost Clementsen, Uffe Bødtger   +3 more
openalex   +1 more source

Effect of an Indwelling Pleural Catheter vs Talc Pleurodesis on Hospitalization Days in Patients With Malignant Pleural Effusion: The AMPLE Randomized Clinical Trial

Journal of the American Medical Association (JAMA), 2017
Rajesh Thomas, E. Fysh, Nicola A. Smith, Pyng Lee, Benjamin C. H. Kwan, E. Yap, Fiona C. Horwood, F. Piccolo, D. C. Lam, Luke A Garske, Ranjan L Shrestha, C. Kosky, C. Read, K. Murray, Y. C. G. Lee   +14 more
semanticscholar   +1 more source

Artificial Intelligence‐Based In Silico Evaluation of the Pharmacological Potential and In Vitro Anti‐Malignancy Effect in the Human Glioblastoma Cell Line of the Hydrate of the Coumarin Compound Meranzin Originating From the Edible Macroalga (Bangia fuscopurpurea)

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
In U87 cells, meranzin hydrate showed cytotoxicity (MIC = 50 μM) and anti‐invasion activity (IC50 = 33.12 μM) but had no inhibitory effect on colony formation. It also suppressed the cancer stem cell property of sphere formation (IC50 = 21.43 μM). In silico analysis indicated that meranzin hydrate may downregulate the protein expression of ALDH1A1 and ...
Shi‐Ying Huang, Yi‐Chen Chang, Charles Chien‐Chih Chiu, Chang‐Wei Hsieh, Chien‐Wei Feng, Zhi‐Cheng Chen, Nan‐Fu Chen, Yung‐Kuo Lee, Tian‐Huei Chu, Cheng‐Chieh Fang, Nan‐Chieh Huang   +10 more
wiley   +1 more source

Intracavitary infusion of FOLactis Lactobacillus leads to disappearance of MPE in patient with advanced lung adenocarcinoma

Discover Oncology
This case report presents the application of FOLactis, a lactic acid bacterium in situ vaccine, in the treatment of a lung adenocarcinoma patient who presented with malignant pleural effusion (MPE).
Mingzhen Zhou, Juan Zhang, Sihui Zhu, Yan Zhao, Baorui Liu, Jie Shen   +5 more
doaj   +1 more source

Managing Treatment‐Emergent Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CAR‐T Cell Therapy: A Case‐Based Review of the use of Emapalumab

Hematological Oncology, Volume 44, Issue 1, January 2026.
ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapies have revolutionized the treatment of hematological malignancies, achieving high response rates in patients with relapsed or refractory disease. Despite these benefits, CAR‐T cell therapies are associated with unique toxicities, including cytokine release syndrome (CRS), immune effector cell ...
Livia Donzelli, Veronica Zullino, Giovanni Fernando Torelli, Maria Stefania De Propris, Mario Piazzolla, Franco Ruberto, Maurizio Martelli, Alice Di Rocco   +7 more
wiley   +1 more source

Robust Diagnostic and Therapeutic Biomarkers for Tuberculosis Identified Through Multi‐Omics and Mendelian Randomization Analysis

MedComm, Volume 7, Issue 1, January 2026.
We performed UPLC‐MS/MS lipidomics and DIA proteomics on plasma from healthy controls, active TB patients, and cured patients, and used Mendelian randomization to prioritize diagnostic and cure biomarkers. Multi‐omics random‐forest models based on these biomarkers showed excellent performance for diagnosis and cure monitoring.
Chenglin Zhu, Jiaxi Chen, Ying Li, Qi Zhang, Qiqi Lu, Ningxuan Zhang, Hao Fan, Muhammad Mahtab Aslam Khan Khakwani, Lei Zhang, Ji‐Cheng Li   +9 more
wiley   +1 more source

Adverse events after pleurodesis in patients with malignant pleural effusion [PDF]

, 2020
Ricardo Mingarini Terra, P. Costa, Alberto Jorge Monteiro Dela Vega, Paulo Manuel Pêgo‐Fernandes   +3 more
openalex   +1 more source

Organoids in Cancer Research and Regenerative Medicine: Current Status, Challenges, and Future Prospects

MedComm, Volume 7, Issue 1, January 2026.
The management of cancer and tissue regeneration remains a substantial challenge to global health. Organoids, which are stem cell‐derived three‐dimensional multicellular structures, are revolutionizing biomedical research. Therefore, this review highlights their applications in cancer research and regenerative medicine, while discussing current ...
Ruiyang Li, Yuezhou Wu, Zhu'anzhen Zheng, Fengjin Zhou, Ke Xu, Jiacan Su   +5 more
wiley   +1 more source