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Malignant pleural effusion [PDF]
QJM, 2013 Malignant pleural effusion (MPE) refers to the presence of neoplastic cells in the pleural fluid. Approximately 40 000 people per year in the UK are affected by MPE and it is associated with significant morbidity and an overall poor prognosis. Management should be prompt and care plans should be individualized and involve a multidisciplinary team of ...
Egan, A. M. +3 more
openaire +3 more sources
BMC Pulmonary Medicine, 2023 Aim To investigate the diagnostic value of combined detection of SHOX2 and RASSF1A gene methylation with carcinoembryonic antigen (CEA) level in diagnosing malignant pleural effusion.
Shaosen Chen +4 more
doaj +2 more sources
Life, 2023 Malignant pleural effusion is associated with a poor prognosis and, while risk stratification models exist, prior studies have not evaluated pleural fluid resolution and its association with survival.
Christina R. MacRosty +5 more
doaj +4 more sources
Egyptian Journal of Chest Disease and Tuberculosis, 2015 Introduction: Distinction between malignant and non-malignant pleural effusion is of great importance in the patient management. The aim: We examined the diagnostic value of C-reactive protein (CRP) and serum amyloid A (SAA) in distinguishing different ...
Hala Mohamed Shalaby Samaha +3 more
doaj +2 more sources
Egyptian Journal of Chest Disease and Tuberculosis, 2016 Background: Despite the fact that Light’s criteria remain the gold standard approach in differentiating exudates from transudates, several fluid markers have been introduced for establishing the cause of pleural effusion to differentiate types of pleural
Heba M. Atef +3 more
doaj +2 more sources
Evaluation of pleural fluid YKL-40 as a marker of malignant pleural effusion
Egyptian Journal of Chest Disease and Tuberculosis, 2015 The glycoprotein YKL-40 is synthesized both by cancer cells and by tumor-associated macrophages and plays a functional role in tumor progression. Consequently, high serum YKL-40 levels have been associated with a poor prognosis in patients with several ...
Adel Attia +3 more
doaj +2 more sources
Management of Malignant Pleural Effusion
Clinical Pulmonary Medicine, 2018 © 2018 Wolters Kluwer Health, Inc. Malignant pleural effusion is a common clinical problem with an increasing incidence that may be seen to complicate the management of almost all forms of cancer. It is associated with a very poor median survival leading to a palliative management approach.
McCracken, D, Rahman, N
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Egyptian Journal of Chest Disease and TuberculosisBackground Pleural effusions can be caused by various diseases, making their diagnosis challenging. Light’s criteria are often used to distinguish transudative and exudative effusions.
Nashwa A. Amin +6 more
doaj +2 more sources
Diagnostic Value of Neutrophil-Lymphocyte Ratio in Exudative Pleural Effusion [PDF]
Al-Azhar International Medical Journal, 2022 Background: As many patients may be unfit to undergo medical thoracoscopy, in addition to the low yield of closed pleural biopsy in malignant conditions, finding novel hematological or pleural fluid biomarkers to unmask the diagnosis of exudative pleural
Houssam Eldin Abd Elnaby +3 more
doaj +1 more source
The significance of Fas, tumor necrosis factor-related apoptosis-inducing ligand and fibrinolytic factors in the assessment of malignant pleural effusion [PDF]
Archives of Biological Sciences, 2022 Few studies have examined the usefulness of soluble apoptotic markers for the screening of pleural effusion. This study aimed to investigate the significance of Fas, tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and fibrinolytic factors
Choi Jong Weon +2 more
doaj +1 more source