Human lung adenocarcinoma cell cultures derived from malignant pleural effusions as model system to predict patients chemosensitivity [PDF]
, 2016 BACKGROUND: Lung cancer is the leading cause of cancer related deaths and Malignant Pleural Effusion (MPE) is a frequent complication. Current therapies suffer from lack of efficacy in a great percentage of cases, especially when cancer is diagnosed at ...
CHERUBINI, EMANUELA +17 more
core +3 more sources
Malignant pleural effusion: current understanding and therapeutic approach
Respiratory ResearchMalignant pleural effusion (MPE) is a common complication of thoracic and extrathoracic malignancies and is associated with high mortality and elevated costs to healthcare systems.
F. Gonnelli +7 more
semanticscholar +1 more source
Development and validation of the PET-CT score for diagnosis of malignant pleural effusion
European Journal of Nuclear Medicine and Molecular Imaging, 2019 PurposeAlthough some parameters of positron emission tomography with 18F-fluorodeoxyglucose (18F-FDG) and computed tomography (PET-CT) are somehow helpful in differentiating malignant pleural effusion (MPE) from benign effusions, no individual parameter ...
Min-Fu Yang +11 more
semanticscholar +1 more source
Tumor Biology, 2017 The differential diagnosis of malignant pleural effusion and benign pleural effusion remains a clinical problem. Reactive oxygen species modulator 1 is a novel protein overexpressed in various human tumors. The objective of this study was to evaluate the
Xianmeng Chen +3 more
doaj +1 more source
Evaluation of pleural fluid YKL-40 as a marker of malignant pleural effusion
Egyptian Journal of Chest Disease and Tuberculosis, 2015 The glycoprotein YKL-40 is synthesized both by cancer cells and by tumor-associated macrophages and plays a functional role in tumor progression. Consequently, high serum YKL-40 levels have been associated with a poor prognosis in patients with several ...
Adel Attia +3 more
doaj +1 more source
Immune modulation in malignant pleural effusion: from microenvironment to therapeutic implications
Cancer Cell InternationalImmune microenvironment and immunotherapy have become the focus and frontier of tumor research, and the immune checkpoint inhibitors has provided novel strategies for tumor treatment.
Shan Ge +10 more
semanticscholar +1 more source
Successful Treatment of Pneumothorax in a Dog With Sterile Pleural Fibrosis Caused by Chylothorax [PDF]
, 2019 A 2-year-old, 12 kg, intact male crossbreed dog was presented with respiratory distress, exercise intolerance, and gagging. Plain thoracic radiographs revealed severe pleural effusion.
Gruber, Achim D. +3 more
core +1 more source
Utility of Emerging Novel Criteria “Cancer Ratio” and “Cancer Ratio Plus” in Differentiating Malignant from Nonmalignant Pleural Effusions [PDF]
Indian Journal of Respiratory CareBackground and objectives: Distinguishing between malignant and benign pleural effusion (including tuberculous pleuritis with effusion) is vital for any patient with an exudative pleural effusion.
Humaira Javaid +5 more
doaj +1 more source
Cell origins and diagnostic accuracy of interleukin 27 in pleural effusions. [PDF]
PLoS ONE, 2012 The objective of the present study was to investigate the presence of interleukin (IL)-27 in pleural effusions and to evaluate the diagnostic significance of pleural IL-27.
Wei-Bing Yang +9 more
doaj +1 more source
Genomic profiling of malignant peritoneal mesothelioma reveals recurrent alterations in epigenetic regulatory genes BAP1, SETD2, and DDX3X. [PDF]
, 2017 Malignant mesothelioma is a rare cancer that arises from the mesothelial cells that line the pleural cavity and less commonly from the peritoneal lining of the abdomen and pelvis.
Bastian, Boris C +10 more
core +2 more sources