Results 21 to 30 of about 58,832 (240)
Evaluation of pleural fluid YKL-40 as a marker of malignant pleural effusion
The glycoprotein YKL-40 is synthesized both by cancer cells and by tumor-associated macrophages and plays a functional role in tumor progression. Consequently, high serum YKL-40 levels have been associated with a poor prognosis in patients with several ...
Adel Attia +3 more
doaj +1 more source
Utility of Emerging Novel Criteria “Cancer Ratio” and “Cancer Ratio Plus” in Differentiating Malignant from Nonmalignant Pleural Effusions [PDF]
Background and objectives: Distinguishing between malignant and benign pleural effusion (including tuberculous pleuritis with effusion) is vital for any patient with an exudative pleural effusion.
Humaira Javaid +5 more
doaj +1 more source
Cell origins and diagnostic accuracy of interleukin 27 in pleural effusions. [PDF]
The objective of the present study was to investigate the presence of interleukin (IL)-27 in pleural effusions and to evaluate the diagnostic significance of pleural IL-27.
Wei-Bing Yang +9 more
doaj +1 more source
Managing malignant pleural effusion
Malignant pleural effusion can be managed in different ways, including clinical observation, thoracentesis, placement of an indwelling pleural catheter, and chemical pleurodesis. The optimal strategy depends on a variety of clinical factors. This article uses cases to illustrate the rationale for determining the best approach in different situations.
Ali Saeed, Wahla +3 more
openaire +2 more sources
Malignant pleural mesothelioma with resolution of pleural effusion
Key message In malignant pleural mesothelioma patients, pleural effusion may improve during the course of the disease. Pleural effusion with nodular shadows bordering the pleura should be followed up even if the pleural effusion improves.
Sayaka Nishida +3 more
doaj +1 more source
Objective. The aim of the study is to investigate the clinical value of matrix metalloproteinases-3 (MMP-3) and cytokeratin 19 fragment antigen 21-1 (CYFRA21-1) combined with adenosine deaminase (ADA) in pleural effusion and serum in benign and malignant
Zhiyang Xu +4 more
doaj +1 more source
Pleural Effusions in Hematologic Malignancies
Nearly all hematologic malignancies can occasionally present with or develop pleural effusions during the clinical course of disease. Among the most common disorders are Hodgkin and non-Hodgkin lymphomas, with a frequency of 20 to 30%, especially if mediastinal involvement is present.
Alexandrakis, MG +3 more
openaire +3 more sources
Diagnostic value of procalcitonin in pleural effusion
Background A wide range of diseases can cause pleural effusion. Its diagnosis and management remain a clinical challenge, bearing a significant cost to both patients and health care system.
Abdelsadek H Al-Aarag +3 more
doaj +1 more source
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang +13 more
wiley +1 more source

