Results 81 to 90 of about 55,955 (202)

The management of malignant pleural effusion [PDF]

Postgraduate Medical Journal, 1973
Summary Several effective methods exist for the control of malignant pleural effusion: the most effective is iodized talc poudrage, but the relatively short survival times associated with malignant effusions from bronchogenic carcinomas make less elaborate methods more appropriate.
openaire   +2 more sources

The 9th International RASopathies Symposium

American Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1934-1941, August 2026.
ABSTRACT The RASopathies are a group of congenital disorders with overlapping clinical manifestations that are caused by pathogenic germline or early somatic variants that result in the hyperactivation of the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway.
Pau Castel, Lisa Schoyer, Beth Stronach, Raya Bogdanova, Anton M. Bennett, Jaishri Blakeley, Miriam Bornhorst, Tammy Bowers, Saskia M. Brachmann, Emma Burkitt‐Wright, Kathryn Chatfield, Alessandro De Luca, Khalil El‐Chammas, Abdul Elkadri, John E. Fortunato, Bruce D. Gelb, Anne Goriely, Karen Gripp, Kassidy Grover, Lindsay Homan, Kenneth A. Kern, Maija Kiuru, Charles (Chuck) Lawson, Yong‐Seok Lee, Frank McCormick, Gina Ney, Cristina Nuevo‐Tapioles, Sara Pardej, Elizabeth I. Pierpont, Julia Plank, Nancy Ratner, Katherine A. Rauen, J. Elliott Robinson, Les Rogers, Sarah E. Sheppard, Keir Shiels, David Stevenson, Dagmar Tiemens, Matthew Traylor, K. Nicole Weaver, Marielle Yohe, Tamar Green   +41 more
wiley   +1 more source

A Phase I/II Study of Ibrutinib Plus Trastuzumab in HER2‐Positive Metastatic Breast Cancer

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Ibrutinib has demonstrated inhibition of ErbB/HER tyrosine kinases in preclinical models. This Phase I/II study investigated the safety, efficacy, and immunomodulatory effects of ibrutinib in combination with trastuzumab in patients with HER2‐positive metastatic breast cancer (MBC) whose disease had progressed on ado‐trastuzumab emtansine ...
Joyce O'Shaughnessy, Andrea Glidden, Tracy Locke, Amy Scales, Elizabeth Gatewood, Jean‐Philippe Blanck, Jessica Castaneda‐Gill, Sharlin Patel, Yolanda D. Mahnke, Xuan Wang, Page Blas   +10 more
wiley   +1 more source

IL‐6 Upregulates CD73 in Human Placental Mesenchymal Stem Cells to Promote ATRA‐Induced NB4 Cell Differentiation in Acute Promyelocytic Leukemia

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Purpose To investigate the expression profile of IL‐6 in patients with acute promyelocytic leukemia (APL) and its role in modulating the ability of hPMSCs to regulate the differentiation of NB4 cells. Methods Peripheral blood samples were obtained from newly diagnosed APL patients and healthy controls.
Rong Qi, Hengchao Zhang, Yunhua Wu, Yanchao Ma, Xiying Luan   +4 more
wiley   +1 more source

Diagnostic Value of Sialic Acid in Pleural Effusion

Chinese Journal of Lung Cancer, 2010
The present study was conducted in 30 patients of malignant pleural effusion and 30 patients of non malignant pleural effusion. Pleural fluid and blood samples were taken at the time of admission, before starting any treatment.
S KHARB, S TANDON, A BANSAL
doaj  

A novel approach in the identification of microRNAs in malignant pleural effusion for lung cancer diagnosis

Oncology Reviews
IntroductionPleural effusion, an atypical accumulation of fluid in the pleural space, has been identified as a potential indicator of several diseases, including lung cancer.
Jesús Valencia-Cervantes, Jesús Valencia-Cervantes, Gustavo Ramirez-Martínez, Margarita Isabel Palacios-Arreola, Alejandra Loaeza-Román, Martha Patricia Sierra-Vargas   +5 more
doaj   +1 more source

From Basics to Benchmarks: Evaluating Sample Adequacy, PD‐L1 Expression, and Molecular Profiling in Effusion Samples of Lung Adenocarcinoma

Diagnostic Cytopathology, Volume 54, Issue 8, Page 547-555, August 2026.
ABSTRACT Introduction Lung adenocarcinoma commonly causes malignant pleural effusion (MPE), a condition with poor prognosis and limited treatment options. Pleural effusion specimens offer a minimally invasive source for diagnosis and molecular testing.
Harpreet Virk, Claire Michael, Keri Ann Pfeil, Navid Sadri, Omid Savari, Aparna Harbhajanka   +5 more
wiley   +1 more source

Risk Factors for Mortality Associated With Influenza Infection in Patients With Hematologic Malignancies: A Cross‐Sectional Descriptive Observational Study

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Cancer patients, especially those with hematologic malignancies (HMs), are considered among the most vulnerable groups at risk for severe outcomes from influenza infection. This study aimed to investigate influenza infection in patients with HMs and identify the risk factors associated with mortality.
Setayesh Sindarreh, Seyed Amirhossein Dormiani Tabatabaei, Mehran Sharifi, Maryam Nasirian, Seyed Hamed Tooyserkani, Fariba Alikhani, Hamide Rahmani Seraji, Arefeh Zamani, Atousa Hakamifard   +8 more
wiley   +1 more source

Macrophage: Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
Macrophages are sentinel innate immune cells that arise from embryonic precursors and bone marrow monocytes, displaying a functional continuum that transcends the classical M1 (pro‐inflammatory)/M2 (anti‐inflammatory) dichotomy. Under homeostatic conditions, balanced M1/M2 polarization preserves tissue integrity by coordinating immune surveillance ...
Bihang Sun, Linqing Wen, Shiyun Tang, Lu Liu, Nianzhi Chen   +4 more
wiley   +1 more source

Successful Diagnostic Confirmation of Malignant Pleural Mesothelioma With Extensive Pleural Adhesions Using Pleural Cryobiopsy Under Local Anaesthesia

Respirology Case Reports, Volume 14, Issue 8, August 2026.
Pleural cryobiopsy under local anaesthesia enabled definitive diagnosis of malignant pleural mesothelioma despite extensive pleural adhesions. Careful preoperative assessment and precise lesion localisation allowed safe and minimally invasive tissue acquisition in a high‐risk patient.
Shotaro Otaki, Mikito Suzuki, Kaito Yano, Tomohiro Imoto, Reiko Shimizu, Tsunekazu Hishima, Kazuo Nakagawa   +6 more
wiley   +1 more source