Results 31 to 40 of about 27,683 (265)

Pathologic diagnosis of malignant mesothelioma: chronological prospect and advent of recommendations and guidelines [PDF]

, 2015
Malignant mesothelioma is rare and difficult to diagnose. Its identification depends upon pathological investigation (cyto-histological assessment and immunohistochemistry) supported by clinical and radiological evidence.
Ascoli, Valeria
core   +2 more sources

Managing malignant pleural effusion

Cleveland Clinic Journal of Medicine, 2019
Malignant pleural effusion can be managed in different ways, including clinical observation, thoracentesis, placement of an indwelling pleural catheter, and chemical pleurodesis. The optimal strategy depends on a variety of clinical factors. This article uses cases to illustrate the rationale for determining the best approach in different situations.
Ali Saeed, Wahla, Mateen, Uzbeck, Yaser Abu, El Sameed, Zaid, Zoumot   +3 more
openaire   +2 more sources

Improved diagnosis and prognostication of patients with pleural malignant mesothelioma using biomarkers in pleural effusions and peripheral blood samples – a short report [PDF]

, 2017
Purpose: There is a lack of robust and clinically utilizable markers for the diagnosis and prognostication of malignant pleural mesothelioma (MPM).
Aerts, J.G.J.V. (Joachim), Bakker, M.A. (Michael) den, Beije, N. (Nick), Cornelissen, R. (Robin), Kraan, J. (Jaco), Leest, K.H. (Cor) van der, Maat, A.W.P.M. (Alex), Martens, J.W.M. (John), Sleijfer, S. (Stefan), van, N.M. (Ngoc M.)   +9 more
core   +1 more source

Mitoxantrone pleurodesis to palliate malignant pleural effusion secondary to ovarian cancer [PDF]

, 2004
Background Advanced ovarian cancer is the leading non-breast gynaecologic cause of malignant pleural effusion. Aim of this study was to assess the efficacy of mitoxantrone sclerotherapy as a palliative treatment of malignant pleural effusions due to ...
FH Hausheer, TJ Lynch, L Saffran, PM Dvoretsky, SA Sahn, WW Johnston, G Antunes, FH Hausheer, E Patz, KG Seaton, D Cheng, DL Hartman, TR Gravelyn, BA Goff, MJ Moffet, MJ Ostrowski, JC Ruckdeschel, DH Rehse, EM Marom, BL Fingar, FS Vargas, D Seitzer, E Musch, AG Maiche, AF Van Belle, M Morales, G Groth   +26 more
core   +2 more sources

Pleural Effusions in Hematologic Malignancies

Chest, 2004
Nearly all hematologic malignancies can occasionally present with or develop pleural effusions during the clinical course of disease. Among the most common disorders are Hodgkin and non-Hodgkin lymphomas, with a frequency of 20 to 30%, especially if mediastinal involvement is present.
Alexandrakis, MG, Passam, FH, Kyriakou, DS, Bouros, D   +3 more
openaire   +3 more sources

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

Experience with indwelling pleural catheters in the treatment of recurrent pleural effusions

Therapeutic Advances in Respiratory Disease, 2016
Recurrent pleural effusions are frequently encountered in clinical practice. Whether malignant or nonmalignant, they often pose a challenge to the practicing clinician.
Michel Chalhoub, Zulfiqar Ali, Louis Sasso, Michael Castellano   +3 more
doaj   +1 more source

Transcriptomic Profiling of Pleural Effusions: Differences in Malignant and Infectious Fluids

Medicina
Background and Objectives: Different cellular and molecular processes are involved in the production of malignant and infectious pleural effusions.
Lucía Zamora-Molina, Eduardo García-Pachón, Marta Amorós, Julia Gijón-Martínez, Judith Sánchez-Almendro, Carlos Baeza-Martínez, Luis Hernández-Blasco, Antonio Galiana   +7 more
doaj   +1 more source

Diagnostic utility of medical thoracoscopy in undiagnosed exudative pleural effusions

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2020
Background: Medical thoracoscopy is a minimally invasive technique to inspect the pleural space and to perform biopsy of pleural lesions under direct vision.
Vikas Marwah, D Bhattacharyya, Mohamed Falih Ali, Ashok Kumar Rajput, Prashant Sengupta, Gaurav Bhati   +5 more
doaj   +1 more source

Common Signatures of Altered Gene Regulation and Invasiveness of Different Breast Cancer Cell Lines after Matrix Interface Crossing

Advanced Healthcare Materials, EarlyView.
Interface transmigration reprograms triple‐negative breast cancer cells, triggering a shared switch toward more aggressive and invasive phenotypes. Using a collagen I interface model, this study identifies shared transcriptional changes involving proliferation, chromatin remodeling, and DNA repair pathways.
Cornelia Clemens, Hannah Trampert, Nataliia Kotsiuba, Tilo Pompe   +3 more
wiley   +1 more source