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Update on Malignant Pleural Mesothelioma
Seminars in Respiratory and Critical Care Medicine, 2011Malignant pleural mesothelioma is an aggressive cancer principally attributable to asbestos. Although the incidence is now declining in the United States, it will continue to increase worldwide until all nations institute regulations limiting asbestos use and exposure.
Nicholas Paul, Campbell +1 more
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Localized malignant pleural mesothelioma
General Thoracic and Cardiovascular Surgery, 2012Localized malignant pleural mesothelioma (LMPM) is a rare tumor; previously only 52 cases have been reported in the English literature. This type of tumor should be distinguished from diffuse malignant pleural mesothelioma, because a good outcome may be obtained by surgical resection. We report a case of LMPM which grew rapidly within 1 year.
Takayuki, Nakano +5 more
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Localized pleural malignant mesothelioma
Pathology International, 2001Pleural malignant mesothelioma (PMM) is a rare tumor and it is commonly seen in the form of multiple nodules or a diffuse tumor. A localized tumor mass in the pleura is extremely rare. Only seven cases have been reported. In this report, we present an additional case of localized PMM and describe the immunohistochemical and flow cytometric findings.
S, Erkiliç, I, Sari, B, Tunçözgür
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Management of Malignant Pleural Mesothelioma
Clinics in Chest Medicine, 2006Malignant mesothelioma is increasing in incidence globally and has no known cure. Its unique clinical feature of local infiltration along tissue planes makes it a difficult neoplasm to manage. There have been few randomized controlled trials regarding treatment options, although these have increased in recent years, and results are eagerly awaited ...
West SD, Lee YCG
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Intradural pleural malignant mesothelioma
Acta Neurochirurgica, 2007Pleural malignant mesothelioma is a rare tumour of the pleural epithelium, which progresses by infiltration into the lung parenchyma, the chest wall, and the mediastinum. Haematogenous spreading may occur in the late stages of the disease. Spinal involvement is exceptional and usually occurs in the vertebral body or epidural space, and intradural ...
M, Payer, T, von Briel
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Pathology of Malignant Pleural Mesothelioma
Thoracic Surgery Clinics, 2020Despite multiple diagnostic toolkits, the diagnosis of diffuse malignant pleural mesothelioma relies primarily on proper histologic assessment. The definitive diagnosis of diffuse malignant pleural mesothelioma is based on the pathologic assessment of tumor tissue, which can be obtained from core biopsy sampling, pleurectomy, or other more extensive ...
Yin P, Hung, Lucian R, Chirieac
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Chemotherapy for Malignant Pleural Mesothelioma
Current Treatment Options in Oncology, 2011All MPM patients with a good performance status should be considered for enrollment on clinical trials. With that said, the standard frontline therapy for fit MPM patients remains an antifolate/platinum doublet, based on large, well powered randomized clinical trials that showed not only a survival benefit for antifolate/platinum regimens but also ...
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Surgery for malignant pleural mesothelioma
Annals of Diagnostic Pathology, 2009Malignant pleural mesothelioma (MPM) remains a challenging disease from the surgical perspective. Its diffuse nature with involvement of the lung, pericardium, and diaphragm; the inability to reliably obtain negative margins; the significant morbidity and mortality associated with radical resection; and most importantly, the high recurrence rate after ...
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Chemotherapy for Malignant Pleural Mesothelioma
Clinical Lung Cancer, 2003Malignant pleural mesothelioma is an aggressive malignancy with no known single curative modality. Most patients are candidates for chemotherapy at some point in their treatment, but no standard regimen has been established. Several phase II single-agent and combination chemotherapy studies have been performed over the past 2 decades. Although the true
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Pemetrexed in Malignant Pleural Mesothelioma
Clinical Cancer Research, 2005Abstract Purpose: This report describes the data and analysis leading to the approval of pemetrexed (LY 231514, MTA, Alimta, Eli Lilly and Co., Indianapolis, IN) by the U.S. Food and Drug Administration (FDA) of a New Drug Application for the treatment of malignant pleural mesothelioma (MPM).
Maitreyee, Hazarika +14 more
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