Results 111 to 120 of about 1,736,515 (318)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Engineering the tumor microenvironment of colorectal cancer [PDF]

open access: yes, 2014
The tumor microenvironment contributes significantly to the clinical prognosis, especially in CRC. Infiltration by cells from the adaptive immune system (e.g. CD8) has been linked to a better survival independently of TNM-stage.
Hirt, Christian Kurt
core   +1 more source

Safety and efficacy of dehydrated ethanol soaking of the operative field in the treatment of spontaneous hepatocellular carcinoma rupture

open access: yesWorld Journal of Surgical Oncology, 2018
Background The aim of our study was to evaluate the clinical safety and value of ethanol surgical field infiltration (ESFI), combined with distilled water peritoneal lavage (DWPL), after hepatectomy in patients with hepatocellular carcinoma (HCC) rupture.
Jian Sun   +8 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

"Ruptured" malignant phyllodes tumor of the breast: a case report [PDF]

open access: yes, 2016
Chagkrit Ditsatham, Areewan Somwangprasert, Kirati Watcharachan, Phanchaporn WongmaneerungDivision of Head, Neck and Breast, Department of Surgery, Chiang Mai University, Chiang Mai, ThailandAbstract: Phyllodes tumor or cystosarcoma phyllodes is a rare ...
Wongmaneerung P   +3 more
core  

Invasion-related circular RNA circFNDC3B inhibits bladder cancer progression through the miR-1178-3p/G3BP2/SRC/FAK axis

open access: yesMolecular Cancer, 2018
Background Increasing evidence has revealed that circular RNAs (circRNAs) play crucial roles in cancer biology. However, the role and underlying regulatory mechanisms of circFNDC3B in bladder cancer (BC) remain unknown.
Hongwei Liu   +7 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Clinico-statistical Study of Malignant Tumors in Oral and Maxillofacial Regions [PDF]

open access: yes, 1995
P(論文)Clinico-statistical observations were made of 48 cases of malignant tumors of the oral and maxillofacial regions from 1978 to 1995 at the Department of Oral Surgery, School of Dentistry, Health Sciences University of Hokkaido.
金澤, 正昭   +23 more
core   +1 more source

The features of valve-preserving intervention in a malignant tumor of the right ventricle of heart [PDF]

open access: yes, 2018
The article presents an unusual case of a metastatic lesion of the right ventricle with malignant neoplasm. Its nature and size was definitively determined during the operation.
O.A. Pishchurin   +6 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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