Results 111 to 120 of about 3,102,237 (314)

Congenital Malignant Rhabdoid Tumor of the Skin-Report of a Case and Review of the Literature

, 2011
Malignant rhabdoid tumor is a well-established clinicopathologic entity occurring classically in the kidney and central nervous system in children . Cutaneous origin has rarely been reported.
YANG, CHIN-YI;SHIH, I-HSIN;KUO, TSENG- TONG;YANG, CHIH-HSUN;HSIAO, CHENG-HSIANG, 楊靜宜;施一新;郭承統;楊志勛;蕭正祥   +1 more
core  

Pleuropulmonary blastoma – primary malignant lung tumor in children

Pleuropulmonary blastoma (PPB) is a primary, malignant tumor in children up to 6 years of age. It is a rare tumor and may cause diagnostic difficulties. A 3-year-old girl was hospitalized due to pneumonia and dyspnea.
Barbara Tejza
core   +1 more source

Engineering the tumor microenvironment of colorectal cancer [PDF]

, 2014
The tumor microenvironment contributes significantly to the clinical prognosis, especially in CRC. Infiltration by cells from the adaptive immune system (e.g. CD8) has been linked to a better survival independently of TNM-stage.
Hirt, Christian Kurt
core   +1 more source

Invasion-related circular RNA circFNDC3B inhibits bladder cancer progression through the miR-1178-3p/G3BP2/SRC/FAK axis

Molecular Cancer, 2018
Background Increasing evidence has revealed that circular RNAs (circRNAs) play crucial roles in cancer biology. However, the role and underlying regulatory mechanisms of circFNDC3B in bladder cancer (BC) remain unknown.
Hongwei Liu, Junming Bi, Wei Dong, Meihua Yang, Juanyi Shi, Ning Jiang, Tianxin Lin, Jian Huang   +7 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Exploring functional mechanisms underlying tumor initiation, EMT and cell migration [PDF]

, 2012
Cancer is one of the leading causes of death. A primary tumor forms when cells start to proliferate in an uncontrolled way and stop reacting to restraining signals.
Gruber, Dorothea Cornelia
core   +1 more source

Safety and efficacy of dehydrated ethanol soaking of the operative field in the treatment of spontaneous hepatocellular carcinoma rupture

World Journal of Surgical Oncology, 2018
Background The aim of our study was to evaluate the clinical safety and value of ethanol surgical field infiltration (ESFI), combined with distilled water peritoneal lavage (DWPL), after hepatectomy in patients with hepatocellular carcinoma (HCC) rupture.
Jian Sun, Yue Zhu, Yao-rong Peng, Wen-bin Li, He-yun Zhang, Zhen-yu Zhou, Lin Wang, An-de Ma, Jie Wang   +8 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Distinct ER and PR expression patterns significantly affect the clinical outcomes of early HER2-positive breast cancer: A real-world analysis of 871 patients treated with neoadjuvant therapy

Breast
Introduction: The impact of distinct estrogen receptor (ER) and progesterone receptor (PR) expression patterns on tumor behavior and treatment outcomes within HER2-positive breast cancer is not fully explored.
Haizhu Chen, Xiujuan Gui, Ziwei Zhou, Fengxi Su, Chang Gong, Shunrong Li, Wei Wu, Nanyan Rao, Qiang Liu, Herui Yao   +9 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source