Results 11 to 20 of about 3,102,237 (314)

Human epididymis protein 4 (HE4) in benign and malignant diseases [PDF]

, 2012
Background: Human epididymis protein 4 (HE4) is described as a useful new biomarker in ovarian cancer. As HE4 is neither tumor nor organ specific, we intensively investigated the occurrence of this protein in female and male patients with various benign ...
Kirschenhofer, Angela, Lenhard, Miriam, Fürst, Sophie, Krocker, Katja, Mayr, Doris, Hofmann, Karin, Burges, Alexander, Hertlein, Linda, Stieber, Petra, Nagel, Dorothea   +9 more
core   +1 more source

Multicenter phase II trial of Camrelizumab combined with Apatinib and Eribulin in heavily pretreated patients with advanced triple-negative breast cancer

Nature Communications, 2022
Therapeutic options for patients with triple-negative breast cancer (TNBC) in later-line setting are limited. Here the authors report the results of a phase 2 clinical trial to evaluate efficacy and safety of the combination of camrelizumab (anti-PD1 ...
Jieqiong Liu, Ying Wang, Zhenluan Tian, Ying Lin, Hengyu Li, Zhaowen Zhu, Qiang Liu, Shicheng Su, Yinduo Zeng, Weijuan Jia, Yaping Yang, Shengqiang Xu, Herui Yao, Wen Jiang, Erwei Song   +14 more
doaj   +1 more source

CCL3 secreted by hepatocytes promotes the metastasis of intrahepatic cholangiocarcinoma by VIRMA-mediated N6-methyladenosine (m6A) modification

Journal of Translational Medicine, 2023
Background Intrahepatic cholangiocarcinoma (ICC) is a malignant disease characterized by onset occult, rapid progression, high relapse rate, and high mortality.
Shurui Zhou, Kege Yang, Shaojie Chen, Guoda Lian, Yuzhou Huang, Hanming Yao, Yue Zhao, Kaihong Huang, Dong Yin, Haoming Lin, Yaqing Li   +10 more
doaj   +1 more source

Cancer-associated fibroblasts-mediated ATF4 expression promotes malignancy and gemcitabine resistance in pancreatic cancer via the TGF-β1/SMAD2/3 pathway and ABCC1 transactivation

Cell Death and Disease, 2021
Cancer-associated fibroblasts (CAFs) contribute to malignant progression and chemoresistance in pancreatic ductal adenocarcinoma (PDAC). However, little is known about the underlying mechanism.
Lusheng Wei, Qing Lin, Yanan Lu, Guolin Li, Leyi Huang, Zhiqiang Fu, Rufu Chen, Quanbo Zhou   +7 more
doaj   +1 more source

MALIGNANT TUMOR OF THE TESTICLE. [PDF]

JAMA: The Journal of the American Medical Association, 1907
The recent report1on this subject calls to mind a similar case coming under my own observation. Patient. —J., a brakeman, applied to me, in May, 1900, for relief of what he had been told was hydrocele. Examination. —The left testicle was found to be enlarged to the size ofa lemon; it was fairly firm and not painful.
openaire   +3 more sources

P neumocystis jirovecii-associated immune reconstitution inflammatory syndrome-like phenomenon in a child with leukaemia: a case report and literature review

BMC Pediatrics, 2022
Background Immune reconstitution inflammatory syndrome (IRIS) refers to the phenomenon of intense immune responses against pathogens in patients with AIDS undergoing antiretroviral therapy to reconstitute immune function, resulting in functional ...
Jia-ying Lei, Han Chen, Dun-hua Zhou, Lu-hong Xu, Jian-pei Fang, You-gang Mai   +5 more
doaj   +1 more source

Features Clinical Course and Treatment of Malignant Tumors in Patients with Pulmonary Tuberculosis

, 2023
Currently, the combination of tuberculosis and malignant tumors is being detected more and more often. Some believe that tuberculosis and malignant tumors are parallel diseases, others that they are antagonists, others that tuberculosis contributes to ...
Malignant tumor, tuberculosis, lung.
core   +1 more source

Cyclophosphamide chemotherapy sensitizes tumor cells to TRAIL-dependent CD8 T cell-mediated immune attack resulting in suppression of tumor growth [PDF]

, 2009
Background: Anti-cancer chemotherapy can be simultaneously lymphodepleting and immunostimulatory. Pre-clinical models clearly demonstrate that chemotherapy can synergize with immunotherapy, raising the question how the immune system can be mobilized to ...
Amy Prosser, Robinson, B.W.S., Currie, A.J., Scalzo, A.A., Joanne Salmons, Robbert G van der Most, Mark J Smyth, Bruce W S Robinson, Salmons, J., Lake, R.A., Smyth Mark J., Andrew J Currie, Amanda L Cleaver, Prosser, Amy, van der Most, R.G., Degli-Esposti, M.A., Salmons, Joanne, Lake, Richard A., Prosser, A., Prosser Amy, Nowak, A.K., Currie, Andrew J., van der Most Robbert G., Smyth, M.J., Robinson Bruce W. S., Lake Richard A., Degli-Esposti, Mariapia A., Scalzo Anthony A., Currie Andrew J., Nowak, Anna K., Sathish Mahendran, Cleaver, Amanda L., Richard A Lake, Nowak Anna K., van der Most, Robbert G., Larma, I., Mahendran, S., Anna K Nowak, Degli-Esposti Mariapia A., Anthony A Scalzo, Cleaver, A.L., Robinson, Bruce W.S., Larma, Irma, Irma Larma, Cleaver Amanda L., Smyth, Mark J., Larma Irma, Mehendran, Sathish, Scalzo, Anthony A., Salmons Joanne, Mahendran Sathish, Mariapia A Degli-Esposti   +51 more
core   +2 more sources

Induction of selective blood-tumor barrier permeability and macromolecular transport by a biostable kinin b1 receptor agonist in a glioma rat model [PDF]

, 2012
Treatment of malignant glioma with chemotherapy is limited mostly because of delivery impediment related to the blood-brain tumor barrier (BTB). B1 receptors (B1R), inducible prototypical G-protein coupled receptors (GPCR) can regulate permeability of ...
Neugebauer Witold, Audrey Fortier, Martin Savard (163526), David Fortin (163586), Tsanaclis Ana-Maria, Céléna Dubuc, Jérôme Côté (163514), Céléna Dubuc (163533), Audrey Fortier (163543), Dubuc Céléna, Gobeil, Fernand, Müller-Esterl Werner, Fortin David, Neugebauer, Witold, Werner Müller-Esterl, Gobeil Fernand, Martin Savard, Fortier, Audrey, Tsanaclis, Ana-Maria, Witold Neugebauer (163552), Fernand Gobeil, Tremblay Luc, Luc Tremblay (163561), Lepage, Martin, Veronica Bovenzi (163520), Müller-Esterl, Werner, Bovenzi Veronica, David Fortin, Jérôme Côté, Ana-Maria Tsanaclis, Martin Lepage (125474), Fernand Gobeil Jr (163594), Savard Martin, Fortier Audrey, Dubuc, Céléna, Tremblay, Luc, Lepage Martin, Côté, Jérôme, Luc Tremblay, Martin Lepage, Ana-Maria Tsanaclis (163574), Bovenzi, Veronica, Savard, Martin, Veronica Bovenzi, Côté Jérôme, Fortin, David, Werner Müller-Esterl (37090), Witold Neugebauer   +47 more
core   +2 more sources

Immunoreactive human chorionic gonadotropin and its free ß-subunit in serum and ascites of patients with malignant tumors [PDF]

, 1992
Human chorionic gonadotropin (hCG) is a clinically relevant marker of trophoblastic and nontrophoblastic malignancies. In the present studies, in addition to determining serum hCG, we investigated the presence and properties of hCG immunoreactivity in ...
Mann, Klaus, Spöttl, Gerald, Jüngst, Dieter, Hörmann, Rudolf, Gerbes, Alexander L.   +4 more
core   +1 more source