Results 81 to 90 of about 3,102,237 (314)
The role of NCAM signaling and its effector protein, [beta]1-integrin, in tumor progression [PDF]
, 2007 Neural Cell Adhesion Molecule (NCAM) is a member of the large family of Ca2+independent, immunoglobulin (Ig)-like cell adhesion molecules. So far, its function in homophilic and heterophilic interactions has been mainly studied in neuronal cells, where ...
Kren, Angelika
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Malignant parotid tumor and facial palsy.
, 2009 OBJECTIVE: To evaluate risk factors for postoperative facial palsy in patients with parotid carcinoma. STUDY DESIGN AND SETTING: We conducted a retrospective chart review of patients with parotid carcinoma who underwent parotidectomy at National Taiwan ...
HUANG, CHUN-CHI;TSENG, FEN-YU;CHEN, ZENG-CHANG;HSU, CHUAN-JEN;KO, JENQ-YUH;LOU, PEI-JEN;CHEN, YUH-SHYANG +1 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
High psychosocial burden in relatives of malignant brain tumor patients. [PDF]
, 2018 OBJECTIVE Not only tumor patients suffer enormously from their disease, also the caregivers are massively affected by the disease of their relatives.
Fischbeck, Sabine +9 more
core +1 more source
Discover OncologyBackground Super-enhancers are specialized transcriptional regulatory elements pivotal for establishing and maintaining cell identity. Since their identification in 2013, SEs have garnered considerable attention as promising therapeutic targets in ...
Wenhao Sun +7 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Molecular Cancer, 2020 Background Recent evidences have shown that circular RNAs (circRNAs) are frequently dysregulated and play paramount roles in various cancers. circRNAs are abundant in central nervous system (CNS); however, few studies describe the clinical significance ...
Jiehua He +10 more
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Malignant Tumor of the Hand [PDF]
, 1999 Malignant tumors of the hand are very rare. Between 1989 and 1998, 17 patients with mailgnant tumors of the hand were evaluated for clinical features, prevalence, treatment and results.
신규호
core