Results 201 to 210 of about 5,196,368 (357)

Genetic Landscape of Solid Malignant Tumors in a Russian Cohort of Patients. [PDF]

Diagnostics (Basel)
Slepov IK, Kopylov ED, Turchin AA, Khmelkova DN, Kaimonov VS, Isaev AA, Deev RV.   +6 more
europepmc   +1 more source

INOPERABLE AND MALIGNANT TUMORS

Annals of Surgery, 1932
openaire   +3 more sources

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Research Progress of LEF1 Gene in Malignant Tumors. [PDF]

Clin Med Insights Oncol
Zhao Y, Pan C, Yang S, Ma X, Yao Y, Li Z, Ma Q, Wang X, Wang C, Nie Z.   +9 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Associations Between Malignant Tumors and Alzheimer's Disease: A Cross-Sectional Study. [PDF]

Brain Behav
Zhang Y, Wang Y, Zhao Y, Xin Y, Zhang L, Shan P, Zhu Y.   +6 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Knowledge, attitudes, and practices regarding nutrition among patients with malignant tumors. [PDF]

Front Nutr
Ren Y, Li J, Wu J, Niu Q, Ren X, Ren Q.
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Current situation and research progress of luteolin in the treatment of gastrointestinal malignant tumors. [PDF]

Discov Oncol
Tu Z, Chu T, Yang P, Guan H, Shu X, Li Y, Teng Y, Xu Y, Shu P.   +8 more
europepmc   +1 more source