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Protective effects of bergenin, the major constituent of Mallotus japonicus, on d-galactosamine-intoxicated rat hepatocytes

Journal of Ethnopharmacology, 2000
This study was designed to investigate the effects of bergenin against D-galactosamine-induced injury in primary cultured rat hepatocytes. Bergenin (100 microM) decreased the release of glutamic pyruvic transaminase and sorbitol dehydrogenase by 62 and 50%, respectively, into hepatocyte medium incubated for 14 h with 1.5 mM galactosamine. Decreased RNA
H K, Lim, H S, Kim, M W, Chung, Y C, Kim
openaire   +2 more sources

Induction and relaxation of extrafloral nectaries in response to simulated herbivory in young Mallotus japonicus plants

Journal of Plant Research, 2017
The disadvantage of induced defenses compared with constitutive defenses is the time during which a plant is vulnerable to herbivory before activation. There is obvious importance in determining the costs and benefits of induced defenses. Some plants produce extrafloral nectaries (EFNs), which attract ants that protect against herbivores, and induce ...
Akira, Yamawo, Nobuhiko, Suzuki
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ChemInform Abstract: CHARAKTERISIERUNG VON AUS DEN BLAETTERN VON MALLOTUS JAPONICUS ISOLIERTEM MALLOPRENOL UND SEINEM LINOLENSAEUREESTER

Chemischer Informationsdienst. Organische Chemie, 1970
AbstractAufgrund von spektroskopischen Untersuchungen der Titelverbindungen und ihrer Derivate werden Malloprenol als (Ia) und der Ester als (Ib) identifiziert.
TOSHIHARU NODA   +3 more
openaire   +1 more source

Antitumor-promoting activity of mallotojaponin, a major constituent of pericarps of Mallotus japonicus.

Oncology, 1994
Mallotojaponin, a major constituent of the pericarps of Mallotus japonicus (Euphorbiaceae), inhibited the action of tumor promoter in vitro and in vivo; it inhibited tumor promoter-enhanced phospholipid metabolism in cultured cells, and also suppressed the promoting effect of 12-O-tetradecanoylphorbol-13-acetate on skin tumor formation in mice ...
Y, Satomi   +3 more
openaire   +1 more source

Gene-Metabolite Network Analysis Revealed Tissue-Specific Accumulation of Therapeutic Metabolites in Mallotus japonicus

International Journal of Molecular Sciences, 2021
Megha Rai, Amit Rai, Hideyuki Suzuki
exaly  

Mallotus japonicus Muell.

2012
Shakhnoza S. Azimova   +1 more
openaire   +1 more source

Effects of bergenin, the major constituent of Mallotus japonicus against D-galactosamine-induced hepatotoxicity in rats.

Pharmacology, 2001
The hepatoprotective effects of bergenin, a major constituent of Mallotus japonicus, were evaluated against D-galactosamine (GalN)-induced liver damage in rats. Bergenin (50, 100 and 200 mg/kg) was given orally once daily for 7 successive days and then GalN 400 mg/kg was injected intraperitoneally to rats at 24 and 96 h after the final administration ...
H K, Lim   +5 more
openaire   +1 more source

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