Results 91 to 100 of about 510,515 (307)

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK Pathways

open access: yesArthritis &Rheumatology, EarlyView.
Objective Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla   +13 more
wiley   +1 more source

Pharmacokinetic modelling of intravenous immunoglobulin in children with primary immunodeficiencies and secondary antibody deficiencies

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Children with primary immunodeficiency (PID) and secondary antibody deficiency (SAD) often require immunoglobulin replacement therapy due to low plasma immunoglobulin G (IgG) levels and recurrent infections. Existing pharmacokinetic models for immunoglobulin in PID patients predominantly focus on adults, with limited attention to ...
Iek Leng Cheng   +4 more
wiley   +1 more source

Overcoming child malnutrition in developing countries: past achievements and future choices [PDF]

open access: yes
"About 167 million children under five years of age —almost one-third of the developing world's children —are malnourished. If they survive childhood, many of these children will suffer from poorer cognitive development and lower productivity. As adults,
Haddad, Lawrence James, Smith, Lisa C.
core  

The Introduction of Anthropometrics into Development and Labor Economics [PDF]

open access: yes, 2004
We trace the introduction of anthropometric indicators into development and labor economics in the late ...
Komlos, John, Meermann, Lukas
core   +2 more sources

Long‐term impact of Elexacaftor/Tezacaftor/ivacaftor on pulmonary, nutritional and metabolic outcomes in homozygous F508del cystic fibrosis patients: A real‐world cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Elexacaftor/tezacaftor/ivacaftor (ETI) has markedly improved cystic fibrosis (CF) outcomes. However, its long‐term impact on nutrition, metabolism and liver health remains underexplored. We assessed 30‐month changes in pulmonary, nutritional, metabolic and inflammatory markers in people with CF (PwCF) homozygous for F508del.
Nicola Perrotta   +5 more
wiley   +1 more source

Malnutrition frequency in surgical patients and its effect on morbidity and mortality

open access: yesActa Medica Alanya, 2018
Aim: To determine the frequency of malnutrition in patients with benign and malignant disease admitted to the general surgery service, evaluate the methods used in recognition of malnutrition and to investigate the role of malnutrition in the development
Yılmaz Güler, Mustafa Tireli
doaj   +1 more source

An observation on the bias in clinic-based estimates of malnutrition rates [PDF]

open access: yes
Clinic-based data on malnutrition are the most readily available for following malnutrition levels and trends in most countries, but there is a bias inherent in clinic-based estimates of malnutrition rates.
Fox, Kristin   +2 more
core  

Ocrelizumab‐induced colitis: VigiBase disproportionality analysis, case reports and literature review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Ocrelizumab is a humanized anti‐CD20 monoclonal antibody used in multiple sclerosis. Since its commercialization, several cases of ocrelizumab‐induced colitis have been reported in the scientific literature. Methods To explore the potential association of ocrelizumab with colitis as an adverse drug reaction (ADR), we conducted a descriptive and ...
Audrey Fresse   +3 more
wiley   +1 more source

Evaluation of malnutrition risk screening in hospitalized children with digestive system diseases—a single-center cross-sectional study

open access: yesFrontiers in Pediatrics
ObjectiveThis study aimed to assess the malnutrition risk of hospitalized children with digestive system diseases and provide evidence for clinical nutritional support.MethodsIn this single-enter cross-sectional study, the modified pediatric malnutrition
Xiaoyu Li   +6 more
doaj   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

open access: yesBMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan   +8 more
wiley   +1 more source

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