Breaking barriers: transitioning from X‐ray crystallography to cryo‐EM for structural studies
This article describes the transition of the Glass laboratory from X‐ray crystallography to single‐particle cryo‐electron microscopy (cryo‐EM) for structural studies of ATAD2B, a large AAA+ ATPase‐ and bromodomain‐containing protein involved in chromatin regulation.
Hassan Zafar +4 more
wiley +1 more source
Randomized double-blind crossover trial of a transdermal maltose dissolvable microneedle patch for topical anesthesia before intravenous cannulation for thalassemia children. [PDF]
Jalal MIA +11 more
europepmc +1 more source
Two novel thermophilic bacteria, Thermincola strain AZ34E and Carboxydocella strain AZ29I, were isolated from hydrothermal environments and shown to oxidise carbon monoxide via the water‐gas shift reaction. Comparative genomic and phylogenetic analyses revealed that all currently described isolates within Thermincola and Carboxydocella each represent a
Anastasia Galani +3 more
wiley +1 more source
A Randomized Controlled Trial Comparing Ferric Carboxy-Maltose With Iron Sucrose Complex for Postpartum Iron-Deficiency Anemia. [PDF]
Sharma C +5 more
europepmc +1 more source
The bZIP63.5 transcription factor, activated by Alternaria alternata stress, directly upregulates zinc‐finger transcription factors (Zn2CyS6 and C2H2 types), which in turn enhance the expression of downstream detoxification and defence‐related genes, collectively improving the biocontrol efficacy of Trichoderma harzianum.
Yongfeng Yang +6 more
wiley +1 more source
Ten novel psychrophilic <i>Flavobacterium</i> species from Tibetan Plateau glaciers define a cryospheric lineage with global cold-origin relatives. [PDF]
Liu Q, Yang LL, Xin YH.
europepmc +1 more source
Biofilm Associated Persistence and Drug Tolerance in Mycobacteria Within Host Microenvironments
ABSTRACT Biofilms formed by mycobacteria, particularly Mycobacterium tuberculosis (Mtb), represent a major challenge in tuberculosis (TB) treatment due to their highly organized structure and their capacity to induce phenotypic drug tolerance. These three‐dimensional bacterial aggregates are embedded in a self‐produced extracellular matrix that ...
Lourdes Serrano Garcia +3 more
wiley +1 more source
Genomic adaptation of an autochthonous cider yeast strain to buckwheat and barley wort under stressful brewing conditions. [PDF]
Podgoršek M +7 more
europepmc +1 more source
Photocatalytic syntheses and evaluation of biological activities of rare disaccharides, 3-O-α-D-glucopyranosyl-D-arabinose. [PDF]
Usuki S +9 more
europepmc +1 more source
Comparative Clinical Outcomes of Iron Sucrose and Ferric Carboxymaltose in the Treatment of Iron Deficiency Anemia. [PDF]
El Nekidy WS +9 more
europepmc +1 more source

