ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias +9 more
wiley +1 more source
Maternal immunity and post-vaccination sero-monitoring in small ruminants for peste des petits ruminants eradication in North Shewa, Ethiopia. [PDF]
Alamerew EA +14 more
europepmc +1 more source
Relay Approach: A Convergent Synthesis of Key Fragments en route to (+)‐Neosorangicin A
A selective synthesis of three key fragments of the antibiotically active (+)‐neosorangicin A is reported, providing a foundation for its convergent total synthesis and proof of strategy via a relay approach. ABSTRACT Herein, we report the synthesis of the three key fragments of the macrolide antibiotic (+)‐neosorangicin A, a compound exhibiting potent
Marvin Wenninger +6 more
wiley +1 more source
[Review of breast self-examination and breast self-awareness]. [PDF]
Bartolome-Moreno C +2 more
europepmc +1 more source
Labeling Strategies for Monitoring Cytoskeleton Dynamics in Cultured Epithelial Cells
ABSTRACT Collective cell migration relies on coordinated cytoskeletal remodeling, yet the impact of live‐cell actin filament probes on these dynamics remains poorly characterized. Here, we systematically compared the performance and cellular effects of fluorogenic jasplakinolide‐based probes, SiR‐actin and SiR‐XActin, with the genetically encoded ...
Victoria Levario‐Diaz +6 more
wiley +1 more source
Adapting Yoga Therapy to Meet the Needs of Inpatients Undergoing Hematopoietic Stem Cell Transplantation: Insights From an International, Multisite, Qualitative Study. [PDF]
Mallaiah S +14 more
europepmc +1 more source
“The Most Difficult Conversations We Have”: Resident Experiences With Pediatric Neuroprognostication
ABSTRACT Objective Pediatric neuroprognostication is often complicated by uncertainty and embedded in high‐stakes medical decisions. For child neurology residents, participation in neuroprognostication can represent key learning experiences but also comes with emotional and ethical challenges, which poses a risk of moral distress.
Grant L. Lin +7 more
wiley +1 more source
Detection of Aedes (Fredwardsius) vittatus Mosquitoes, Yucatán Peninsula, Mexico, 2025. [PDF]
Chan-Chable RJ +3 more
europepmc +1 more source
A ramp‐based phase‐locked loop (RPLL) active rectifier operating at 40.68 MHz compensates switching delay variations to improve phase alignment. The proposed architecture achieves 90.3% peak power conversion efficiency and 98.0% voltage conversion ratio for high‐frequency wireless power transfer in implantable medical devices.
Woorim Lee +5 more
wiley +1 more source
Intégration régionale et investissements directs étrangers en Afrique
Hamimida Mama
doaj +1 more source

