ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias +9 more
wiley +1 more source
The Production of Clitics in Serbian Speakers with Stroke Aphasia. [PDF]
Vukovic M, Lukic S.
europepmc +1 more source
Coupling Fluid Neutrals to Gyrokinetic Plasma Dynamics for Edge and SOL Turbulence Simulations
ABSTRACT Accurate modeling of turbulent transport in magnetic confinement fusion devices requires extending first‐principles gyrokinetic simulations from the core to the edge and scrape‐off layer (SOL), where additional physics—particularly plasma–neutrals interactions—must be included.
Sabine Ogier‐Collin +3 more
wiley +1 more source
Hepatic Encephalopathy in the Hepato-Gastroenterology and Internal Medicine Department of General Idrissa Pouye Hospital: A Retrospective Prognostic Study of 69 Cases. [PDF]
Toure B +7 more
europepmc +1 more source
The impact of forced closure on proppant distribution of hydraulic fracturing in shale formations
Research findings demonstrate that implementing forced closure within shale formations can remarkably mitigate proppant settlement, concurrently increasing the effective propped surface area from 29.74% to 38.68%. Abstract Forced closure is widely used in conventional oil and gas reservoirs to promote uniform proppant placement.
Tongxuan Gu +3 more
wiley +1 more source
Association of remittances with skilled delivery in Uganda, 2019/2020. [PDF]
Ducille C +4 more
europepmc +1 more source
Role of SoxE transcription factors in development and disease
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley +1 more source
Dispersive Liquid-Liquid Microextraction Method Utilizing a Novel Peripherally Tetra-Substituted Ni(II) Phthalocyanine as a Sensor Prior to UV-Visible Spectrophotometry for the Determination of Co<sup>2</sup>. [PDF]
Çağlar Y, Saka ET.
europepmc +1 more source

