Results 201 to 210 of about 377,358 (296)

Chemotherapeutic Potential of Fluorouracil‐Platinum (IV) Prodrugs Against Cisplatin‐Resistant Colorectal Cancer Cells

open access: yesChemistry – A European Journal, EarlyView.
ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias   +9 more
wiley   +1 more source

Coupling Fluid Neutrals to Gyrokinetic Plasma Dynamics for Edge and SOL Turbulence Simulations

open access: yesContributions to Plasma Physics, EarlyView.
ABSTRACT Accurate modeling of turbulent transport in magnetic confinement fusion devices requires extending first‐principles gyrokinetic simulations from the core to the edge and scrape‐off layer (SOL), where additional physics—particularly plasma–neutrals interactions—must be included.
Sabine Ogier‐Collin   +3 more
wiley   +1 more source

The impact of forced closure on proppant distribution of hydraulic fracturing in shale formations

open access: yesDeep Underground Science and Engineering, EarlyView.
Research findings demonstrate that implementing forced closure within shale formations can remarkably mitigate proppant settlement, concurrently increasing the effective propped surface area from 29.74% to 38.68%. Abstract Forced closure is widely used in conventional oil and gas reservoirs to promote uniform proppant placement.
Tongxuan Gu   +3 more
wiley   +1 more source

Association of remittances with skilled delivery in Uganda, 2019/2020. [PDF]

open access: yesPLOS Glob Public Health
Ducille C   +4 more
europepmc   +1 more source

The Crash

open access: yes, 2012
Kreuter, Amanda C.
core   +1 more source

Role of SoxE transcription factors in development and disease

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

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