Results 201 to 210 of about 54,137 (281)

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

open access: yesiNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu   +22 more
wiley   +1 more source

Black phosphorus‐based photothermal disruption of cancer‐associated fibroblast barriers and tumor‐associated macrophage targeting to enhance anti‐PD‐L1 immunotherapy in triple‐negative breast cancer

open access: yesInterdisciplinary Medicine, EarlyView.
MBB modulates the TNBC tumor microenvironment by targeting TAM/CXCL1 and facilitates anti‐PD‐L1 therapy by disrupting CAF barriers via its photothermal effect. This combined strategy subsequently enhances the efficacy of PD‐L1 mAb and suppresses TNBC progression, metastasis, and recurrence.
Bo Pan   +12 more
wiley   +1 more source

Targeting eIF5A combats breast cancer progression by ClpP‐dependent mitochondrial oxidative stress

open access: yesInterdisciplinary Medicine, EarlyView.
This study identified the eIF5A‐ClpP axis as a key driver of breast cancer progression. Targeting eIF5A suppresses tumor growth by inducing ClpP‐dependent mitochondrial oxidative stress, revealing a novel therapeutic vulnerability. Abstract Breast cancer (BC) poses a persistent global health challenge, necessitating new therapeutic targets.
Jinmei Zhu   +13 more
wiley   +1 more source

Effectiveness of Interventions for Interpersonal Functioning Among Adolescents With Posttraumatic Stress Symptoms: A Meta‐Analysis

open access: yesJournal of Adolescence, EarlyView.
ABSTRACT Introduction Adolescents with posttraumatic stress symptoms often experience interpersonal difficulties; however, the effectiveness of existing interventions in improving interpersonal functioning remains unclear. This meta‐analysis aimed to evaluate the effectiveness of current interventions on interpersonal functioning among adolescents with
Sabrina Ee‐Ying Ong   +3 more
wiley   +1 more source

Lactation, Childrearing, and Gender Justice

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT In this article, I discuss the significance of early infant feeding choices for the goal of gender justice. Focusing on human lactation practices, I identify Exclusive Gestational Nursing (EGN) as the norm in advanced industrial societies, which creates the expectation and permission for gestators, and only gestators, to nurse children, and ...
Jenny Brown
wiley   +1 more source

Optimization of bioactive compounds extraction from Rosa canina L. pseudofruit through the action of two hydrolytic enzyme preparations

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKROUND The pseudo‐fruit of Rosa canina L. is a rich source of bioactive compounds with antioxidant, anti‐inflammatory, anti‐cancer, anti‐diabetic, anti‐aging, and antimicrobial activities. The aim of the present study is the optimization of a green process based on the action of two hydrolytic enzyme preparations, namely Pectinex® Ultra ...
Zafeiria Lemoni   +6 more
wiley   +1 more source

Using body mapping to explore perceptions of resilience with 7–12‐year‐old Muslim children in East London: A qualitative study

open access: yesJCPP Advances, EarlyView.
This study explored resilience in Black and South Asian Muslim children aged 7–12 in East London, an underrepresented group affected by deprivation and discrimination. Using body mapping, children depicted resilience as personal strength and described the importance of support systems.
Aisling Murray   +6 more
wiley   +1 more source

Australia's Three System Approach to Mammographic Image Quality Assessment

open access: yesJournal of Medical Radiation Sciences, EarlyView.
Mammographic image evaluation in Australia remains constrained by the use of fragmented, subjective, and largely unevaluated systems. The continued use of the Perfect (P), Good (G), Moderate (M), Inadequate (I) (PGMI) image evaluation system (IES) framework despite concerns around its validity and reliability reflects a perceived practical utility and ...
Kelly Bentley‐Spuur, Minh T. Chau
wiley   +1 more source

Sonographic localisation of lymph nodes suspicious of metastatic breast cancer to surgical axillary levels

open access: yesJournal of Medical Radiation Sciences, Volume 72, Issue 1, Page 119-138, March 2025.
Sonographic imaging is used to identify the presence, number and location of malignant lymph nodes. Axillary lymph nodes suspicious of harbouring breast cancer metastasis can be localised to three surgical axillary levels. This paper will unpack the axillary anatomy, muscular sonographic landmarks, surgical axillary lymph node levels and the ...
Michelle Fenech   +4 more
wiley   +1 more source

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