Results 141 to 150 of about 327,828 (356)
A GUIDE TO THE BIRDS AND MAMMALS OF COASTAL PATAGONIA [PDF]
Fabián M. Jaksić
openalex +1 more source
ORGANIC FARMS AS REFUGES FOR SMALL MAMMAL BIODIVERSITY [PDF]
Habitat fragmentation, the process by which relatively continuous habitats is broken into smaller pieces, occurs in natural systems but is to a high degree also human- induced through landscape use.
Hansen, Tine Sussi +2 more
core
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Study of the endocranium and ecology of Eurotherium theriodis, a European hyaenodont mammal from the Lutetian [PDF]
Morgane Dubied +2 more
openalex +1 more source
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Shipping Through Sea Ice: Impacts on Marine Habitats and Best Practices [PDF]
As the result of Arctic climate change and an increase in shipping season length, there is a growing interest in Arctic shipping operations. Sea ice serves as an important habitat for marine mammals, therefore, shipping through sea ice could lead to ...
core
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili +2 more
wiley +1 more source
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Mailliard on Field Work in Northern California in 1921 Field Work among the Birds and Mammals of the Northern Coast of California in 1921 Joseph Mailliard [PDF]
W. S., W. S.
openalex +1 more source

