Results 111 to 120 of about 1,470,106 (385)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Trans-Atlantic movements of Atlantic white-sided dolphins, Leucopleurus acutus

open access: yesFrontiers in Marine Science
Atlantic white-sided dolphins are wide-ranging and abundant cetaceans of the North Atlantic, yet their movements remain poorly understood. Using satellite telemetry, we tracked 23 dolphins tagged in the Faroe Islands to investigate their movement ...
Sara De Clerck   +6 more
doaj   +1 more source

Historic and Current Use of Lower Cook Inlet, Alaska, by Belugas, Delphinapterus leucas [PDF]

open access: yes, 2000
Dedicated at-sea surveys for marine birds and mammals conducted in lower Cook Inlet in late July and early August from 1995–99 failed to locate any belugas, Delphinapterus leucas.
Piatt, John F., Speckman, Suzann G.
core  

Allotopic expression of mitochondrial-encoded genes in mammals: achieved goal, undemonstrated mechanism or impossible task? [PDF]

open access: gold, 2010
Ester Perales‐Clemente   +4 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Hierarchy in Structuring of Resource Selection: Understanding Elk Selection Across Space, Time, and Movement Strategies

open access: yesEcology and Evolution
Movement is a fundamental aspect of animal ecology that varies across space, time, and among individuals or groups within a population. Broad‐scale patterns of animal movement are often classified into different movement strategies, such as resident ...
Storm Crews   +7 more
doaj   +1 more source

Bushmeat hunting and extinction risk to the world's mammals

open access: yesRoyal Society Open Science, 2016
Terrestrial mammals are experiencing a massive collapse in their population sizes and geographical ranges around the world, but many of the drivers, patterns and consequences of this decline remain poorly understood.
W. Ripple   +14 more
semanticscholar   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Catalog of Osteological Collections of Aquatic Mammals from Mexico [PDF]

open access: yes, 1991
This paper compiles available information on osteological and other anatomical specimens of at least 51 species of aquatic mammals (34 extant, one recently extinct and 16 fossil) collected in Mexico between 1868 and 1990 and housed in 29 scientific ...
Vidal, Omar
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

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