Results 181 to 190 of about 703,021 (261)

Chemoproteomic Identification of AKT2 as a Paclitaxel‐Binding Protein via C─C Bond‐Linked Probe PTX‐4 in Paclitaxel‐Resistant Breast Cancer

Advanced Science, EarlyView.
ABSTRACT Breast cancer remains one of the most prevalent malignancies among women, and taxane‐based chemotherapies such as paclitaxel and docetaxel are central to standard treatment regimens. However, drug resistance in breast cancer limits therapeutic efficacy and contributes to recurrence and metastasis.
Kai Wang, Yuqing Yuan, Wei Shen, Xiuxiu Yang, Xiaokang Wu, Haihua Zhou, Yi Hu, Qing Zhu   +7 more
wiley   +1 more source

New records of tick-host mammal interactions (Acari: Ixodidae) in two conservation units of the Brazilian Amazon. [PDF]

Rev Bras Parasitol Vet
Costa IND, Garcia MV, Aguirre LCS, Valença GM, Santos VPD, Costa NVC, Carioca ALPM, D'Andrea PS, Andreotti R, Medeiros JF, Aguirre AAR.   +10 more
europepmc   +1 more source

Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light

Advanced Science, EarlyView.
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley   +1 more source

Stereotyped Whistles May Be First Evidence to Suggest the Possibility of Signature Whistles in an Injured Indo-Pacific Humpback Dolphin (Sousa chinensis) (vol 43, pg 185, 2017)

, 2018
Cheng, Zhaolong, Ding Wang, Zhaolong Cheng, Wu, Haiping, Kexiong Wang, Huang, Shiang-lin, Haiping Wu, Wang, Ding, Shiang-lin Huang, Matthew K. Pine, Wang, Kexiong, Pine, Matthew K., Chongwei Peng, Peng, Chongwei   +13 more
core   +1 more source

Comparative study of the role of nitric oxide in the regulation of food intake across vertebrates. [PDF]

J Vet Sci
Zarei S, Baghbanzadeh A.
europepmc   +1 more source

Charting Endocrine Progenitors Across Species and Organs

Advanced Science, EarlyView.
Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing, Michael Sterr, Özüm Sehnaz Caliskan, Lama Saber, Nicole Katarina Rogers, Samuel Ogden, Kei Kozawa, Christos Karampelias, Jessica Jaki, Aimée Bastidas‐Ponce, Falk Janos Farkas, Oliver Czarnecki, Osvaldo Rodrigues Pereira, Perla Cota, Valerie Vandenbempt, Diego Balboa, Anika Böttcher, Natalie Krahmer, Mohammad Lotfollahi, Julie B. Sneddon, Heiko Lickert, Mostafa Bakhti   +21 more
wiley   +1 more source

Single Applications of Commercial Mammal Deterrents Fail to Prevent Chewing Damage to Passive Acoustic Sensors. [PDF]

Sensors (Basel)
Goodman BD, Chronister LM, Rhinehart TA, Lyon RP, Kitzes J.   +4 more
europepmc   +1 more source

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

Advanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

Temperature-Associated Variation in Evolutionary Rates of <i>FADS1</i> and <i>FADS2</i> in Rodents. [PDF]

Animals (Basel)
Zhao C, Liu Z, Ding X, Xia T, Dai S, Liu G, Fang J, Zhang H.   +7 more
europepmc   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source