Results 201 to 210 of about 516,150 (266)

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Impact of habitat modifications on flea (Siphonaptera) infestation dynamics of non-volant small mammals across wildlife-human interfaces in Tanzania. [PDF]

Int J Parasitol Parasites Wildl
Msoffe VT, Mwombeki FK, Thomas CA, Lyimo CM, Katakweba AS, Misinzo G, Mnyone LL.   +6 more
europepmc   +1 more source

VDAC1 Upregulation Induces Hyperexcitability of Nociceptive Sensory Neurons Via Enhanced Mitochondrial Atp Efflux in Neuropathic Pain

Advanced Science, EarlyView.
The mechanism diagram of VDAC1 mediating neuronal excitability and neuropathic pain. Briefly, VDAC1 is expressed in DRG neurons and is upregulated following CCI‐induced neuropathic pain. This upregulation enhances ATP transport from mitochondria to the cytoplasm in sensory neurons, leading to increased neuronal excitability and pain behavior.
Fengrun Sun, Ning Yu, Liang Yu, Xiaofen Tian, Yujia Ma, Yikuan Xie, Tao Wang, Chao Ma   +7 more
wiley   +1 more source

Life history optimization and the macroevolution of mammal body size. [PDF]

Sci Rep
da Silva J.
europepmc   +1 more source

Radiotherapy Enhances the Oncolytic Efficacy of the Novel Oncolytic Herpesvirus VG161 and Amplifies Its Antitumor Immunity in Breast Cancer

Advanced Science, EarlyView.
RT promotes VG161 replication in BC and its immunostimulatory transgenes expression, which is mediated by the upregulation of GADD34 and HVEM caused by RT. The combination therapy with VG161 and RT increases the abundances of tumor‐infiltrating lymphocytes and elicits potent systemic antitumor immunity, thereby effectively inhibiting local tumors and ...
Lijuan Lyu, Ming Yi, Ji Chen, Zeda Zhao, Ruocen Liao, Yingnan Wang, Shengtao Hu, Jun Ding, Ronghua Zhao, William Jia, Yinan Shen, Yongchang Wei, Kongming Wu, Zhijun Dai   +13 more
wiley   +1 more source

Integrating Niche Dimensions to Advance the Ecological Study of the Americas' Smallest Cat: The Guigna in Argentine Patagonia. [PDF]

Ecol Evol
Guerisoli MM, Bauer G, Sarra Pistone S, Buffa E, Bonaglia C, Giordano AJ, Schiaffini MI.   +6 more
europepmc   +1 more source

DNA Methylation Dynamics in Development and Disease: Insights from Zebrafish Models. [PDF]

Biomedicines
Lai GQ, Yan Y, Sengupta M, Xu TH.
europepmc   +1 more source

Chromosome-level genome assembly of the common tenrec, Tenrec ecaudatus (Schreber, 1778), a new model for early placental mammal evolution. [PDF]

BMC Genomics
Hernández-Roco D, Leushkin E, Galeas J, Grabek KR, Lopez C, Smith GR, Stadtmauer DJ, Wagner GP, van Breukelen F, Hiller M, Goodman L, Arnold P.   +11 more
europepmc   +1 more source

The enigma of inverted lymph node architecture in pigs: insights into immune function and vaccination design. [PDF]

Front Immunol
Larcher T, Picault S, Bed'Hom B, Dubreil L, de La Bernardie X, Schwartz-Cornil I, Bertho N.   +6 more
europepmc   +1 more source

Surveillance of Zoonotic Pathogens and Taxonomic Identification of Non-volant Small Mammals in Peninsular Malaysia. [PDF]

Trop Life Sci Res
Siew ZY, Zariman NF, Sa'idi WSMW, Lui ZY, Coomarhesan HSM, Seow I, Shafie NJ, Wong ST, Razak MFAA, Gani M, Sindang SW, Voon K.   +11 more
europepmc   +1 more source