Results 261 to 270 of about 703,473 (291)

Evolution of Ocular Organ‐On‐Chip Systems for Disease Modelling and Drug Testing: Where are We Now?

open access: yesAdvanced Therapeutics, EarlyView.
The rise in ophthalmic diseases due to aging, screen use, and environmental factors has driven demand for better ocular models. Traditional systems fall short, encouraging the development of organ‐on‐chip devices. These microfluidic platforms replicate eye tissue architecture, enable drug screening, and simulate ocular diseases.
Sara Trujillo
wiley   +1 more source

Role of the Setae in an Ectoparasitic Seal Louse in Reducing Surface Drag: Numerical Modeling Approach

open access: yesAdvanced Theory and Simulations, EarlyView.
The seal louse Echinophthirius horridus has uniquely shaped setae that may reduce drag during its host's dives. Using numerical simulations, this study demonstrates that their natural inclination promotes vortex formation, minimizing friction and energy loss. These findings provide insights into biological surface adaptations and may inspire the design
Anika Preuss   +3 more
wiley   +1 more source

Stereotyped Subclones Revealed by High‐Density Single‐Cell Lineage Tracing Support Robust Development

open access: yesAdvanced Science, EarlyView.
Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang   +14 more
wiley   +1 more source

Self‐Adjusting Engineered Probiotic for Targeted Tumor Colonization and Local Therapeutics Delivery

open access: yesAdvanced Science, EarlyView.
Zou et al. developed an engineered strain of Escherichia coli Nissle 1917 with precise targeting abilities for colonization and on‐demand payload release. The engineered probiotic survives and embolizes tumors only in the presence of more than 5 mM L‐lactate. Furthermore, the introduction of an α‐hemolysin circuit enhances its anti‐tumor effect.
Zhen‐Ping Zou   +8 more
wiley   +1 more source
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Mammals

2000
Costa Rica is one of the most biotically diverse countries on earth, with 4% of known terrestrial plant and animal species in only 0.04% of the world’s land surface. The country’s mammal fauna is equally diverse, with more than 207 species (4.8% of the world’s 4629 species) in an area of 51,022 km2.
Timm, Robert M., LaVal, Richard K.
openaire   +2 more sources

Mammals

2019
(Uploaded by Plazi for the Bat Literature Project) No abstract provided.
Lew, Daniel, K. Lim, Burton
openaire   +2 more sources

Aposematism in mammals

Evolution, 2021
Aposematic coloration is traditionally considered to signal unpalatability or toxicity. In mammals, most research has focused on just one form of defense, namely, noxious anal secretions, and its black-and-white advertisement as exemplified by skunks.
Tim Caro   +6 more
openaire   +4 more sources

Polyspermy in Mammals

Nature, 1953
POLYSPERMY—the entry of more than one sperm into the vitellus at fertilization—is commonly regarded as a pathological process in mammals, with the implication that it leads to early degeneration of the embryo, and this opinion has been expressed by such authorities as Lams1, Wilson2, and Hartman3.
A. W. H. Braden, C. R. Austin
openaire   +3 more sources

Ageing of Mammals

Nature, 1971
In his theory of ageing Professor Bullough suggests that in mammals it is stress which delays cell death through its effect on the chalone mechanism.
openaire   +4 more sources

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