Results 181 to 190 of about 369,864 (299)

The H19/miR‐760/BST2 regulatory axis sustains breast cancer tumorigenesis and metastasis

The FEBS Journal, EarlyView.
H19 and BST2 promote breast cancer aggressiveness through their reciprocal coregulation by miR‐760. Since both transcripts are targeted by miR‐760, overexpression of one sequesters the microRNA and relieves repression of the other: H19 raises BST2 levels, and BST2 raises H19 levels.
Kekely Klouyovo, Evodie Peperstraete, Léa Mabille, Joséphine Louvieaux, Jim Marmuse, Clément Lecerf, Chann Lagadec, Xuefen Le Bourhis, Éric Adriaenssens   +8 more
wiley   +1 more source

Breast mammary gland dataset (BMGD): DAPI-stained fluorescent images for nuclei segmentation. [PDF]

Data Brief
Tasneem Z, Zhao J, Fang J, Shrestha A, Cheng Q.   +4 more
europepmc   +1 more source

RLIM‐associated neurodevelopmental disorders: From clinical spectrum to molecular mechanisms

The FEBS Journal, EarlyView.
RLIM (RNF12) is an E3 ubiquitin ligase essential for mammalian development. Loss‐of‐function variants cause Tønne–Kalscheuer syndrome, while duplications cause Xq13 duplication syndrome, highlighting RLIM dosage sensitivity. This review summarizes the genetics, clinical features, and molecular mechanisms of RLIM‐associated disorders, integrating ...
Madison Landon, Kyra Swildens, Vera M. Kalscheuer, Cristina Gontan, Francisco Bustos   +4 more
wiley   +1 more source

Can cytology accurately predict the malignancy of feline mammary gland tumours? [PDF]

Vet Evid
Virtanen J.
europepmc   +1 more source

Novel targets in headache: A narrative review

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background This narrative review summarizes novel applications for the use of calcitonin gene‐related peptide (CGRP)‐targeted therapies that go beyond migraine, the latest updates with respect to targeting pituitary adenylate cyclase‐activating peptide (PACAP) as therapeutic in migraine, as well as exploring other more recently ...
Adriana Della Pietra, Peter J. Goadsby, Carolina Oldoni, Stephen Silberstein, Fred Cohen, Simon Akerman   +5 more
wiley   +1 more source

Evaluation of Anti-Tumorigenic Effects of Curcumin and Baicalein in 7,12-Dimethylbenz[a] Anthracene-Induced Mammary Gland Tumorigenesis in Wistar Rats. [PDF]

J Biochem Mol Toxicol
Syal P, Singh ND, Devi Leishangthem G, Banga HS.   +3 more
europepmc   +1 more source

Novel and emerging skin carcinomas and adnexal tumours

Histopathology, EarlyView.
The present review aims to provide an overview of the main emerging skin epithelial tumours, with particular emphasis on salivary gland analogue sweat gland tumours and poorly differentiated carcinomas. Epidermal and adnexal tumours of the skin constitute a complex and heterogeneous group of neoplasms, with distinct morphology and behaviour.
Thibault Kervarrec, Maxime Battistella, Nicolas Macagno   +2 more
wiley   +1 more source

Mammary Gland Tropism and Milk-Mediated Transmission of H5N1 in Dairy Cattle: Implications for One Health Surveillance. [PDF]

Vet Sci
Zhang K, Wang Y, Wang X, Wang F, Xu G, Wang J, Wang Z, Cheng Y, Wang H, Yan Y, Sun J, Ma J.   +11 more
europepmc   +1 more source

Milk‐Derived Signals Guide Neonatal Hematopoiesis and Respiratory Defense

Immunology &Cell Biology, EarlyView.
This commentary summarises a recent paper in Cell by Howard et al. showing that osteopontin shapes the infant microbiome, which in turn directs early immune development in the airways. This early programming confers protection against respiratory tract infections that persists well beyond infancy.
Jonatan Leffler, Nivedithaa Divakara, Valerie Verhasselt   +2 more
wiley   +1 more source

Immunomodulatory Peptide LW‐9 Enhances Doxorubicin Efficacy by Downregulating PD‐L1 and Promoting Intratumoral T‐Cell Responses in Murine Breast Cancer

Immunology, EarlyView.
LW‐9, a peptide derived from Phoneutria nigriventer venom, enhances antitumor immunity in a murine breast cancer model by remodelling the tumour microenvironment. Treatment reduces PD‐L1 expression while increasing CD3+ and GITR+ T‐cell infiltration, resulting in delayed tumour progression, particularly when combined with doxorubicin.
Ingrid Mayara Cavalcante Trevisan, Cibele Pereira Mariano, Sabrina Carvalho Brunelli, Gabriel da Silva Cordeiro, Jessika Takaki, Valquiria Aparecida Matheus, Liana Verinaud, Catarina Rapôso   +7 more
wiley   +1 more source