Results 231 to 240 of about 369,864 (299)

Safety and Feasibility of Infusing Ex Vivo Expanded Allogeneic Canine Natural Killer Cells for the Treatment of Metastatic Solid Tumours

open access: yesVeterinary and Comparative Oncology, Volume 24, Issue 4, Page 745-755, December 2026.
ABSTRACT Companion canines need advances in therapeutic options for solid tumour malignancies. Natural killer (NK) cell infusions offer a promising treatment modality in canines with solid tumours. Autologous natural killer products are limited by dysfunctional immunity and a manufacturing process that delays care whereas allogeneic NK cells offer the ...
Allison M. Weisnicht   +11 more
wiley   +1 more source

Expression of Topoisomerase II Alpha in Canine Colorectal Polyps, Adenomas and Adenocarcinomas

open access: yesVeterinary and Comparative Oncology, Volume 24, Issue 4, Page 781-789, December 2026.
ABSTRACT With the development and increased accessibility of diagnostic methods in veterinary medicine, the possibilities for early detection of proliferative lesions in the canine large intestine have expanded over the past decade. Since in human medicine, topoisomerase II alpha (Topo IIα) is considered a prognostic and predictive marker in various ...
Joanna Fiedorowicz   +3 more
wiley   +1 more source

Immunohistochemical Characterisation of Mismatch Repair Proteins in Feline Cancers: A Pilot Study Using Validated Cross‐Reactive Antibodies

open access: yesVeterinary and Comparative Oncology, Volume 24, Issue 4, Page 809-818, December 2026.
ABSTRACT DNA mismatch repair (MMR) deficiency is a clinically important biomarker in human oncology, yet its relevance in feline neoplasia remains poorly understood due to limited characterisation and the absence of validated reagents. In this study, we established a practical immunohistochemistry (IHC) approach for evaluating feline MMR proteins by ...
Shoma Nishibori   +7 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, Volume 20, Issue 11, Page 2805-2819, November 2026.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Mammary Gland Microbiota in Benign Breast Diseases. [PDF]

open access: yesInt J Mol Sci
Ukraincev NI   +4 more
europepmc   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 41, 6 November 2026.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj   +23 more
wiley   +1 more source

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