Results 131 to 140 of about 71,975 (282)

Circ_0006174 Drives Triple Negative Breast Cancer Progression and Immune Escape Through Regulating miR‐3139/PD‐L1 Axis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) is characterized as an aggressive malignancy with limited therapeutic options. The circular RNA circ_0006174 has been implicated in oncogenic processes across various cancers; however, its specific role in the pathogenesis of TNBC remains unclear.
Yong‐Zhe Tang, Li Yang, Ling Wang, Xiao‐Qing Zhang, Jie Wang   +4 more
wiley   +1 more source

Human mammary glands in mice [PDF]

Nature Reports Stem Cells, 2008
openaire   +1 more source

Combined Effects of Puerarin and Adipose‐Derived Stem Cells on Alveolar Bone Preservation and Inflammation Control in Periodontitis Through p38MAPK Modulation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study evaluated the effects of puerarin and adipose‐derived stem cells (ADSCs), alone or combined, on p38MAPK activity, alveolar bone preservation, and inflammatory responses in a rat periodontitis (PD) model and in vitro. ADSCs were exposed to various puerarin concentrations to assess cell proliferation, osteogenic differentiation, and ...
Ting Yang, Xu Zhang, Liang‐Fu Zhang
wiley   +1 more source

Substance P a potent prognostic indicator for canine mammary tumours- a comparative study

Journal of Veterinary and Animal Sciences
Substance P, a neurotransmitter in the central and peripheral nervous system, is considered as a biomarker of pain due to its key role in nociception. But recent researches have proved the increased expression of Substance P and its receptors in
Soumya Ramankutty, S, Anoop, Syam K. Venugopal, M. K. Narayanan, A. R. Nisha, G. Radhika   +5 more
doaj   +1 more source

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, EarlyView.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

Intra-mammary molecular mechanisms involved in the response to changes in milking frequency : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Animal Science at Massey University, Palmerston North, New Zealand [PDF]

, 2015
In dairy cows, short-term changes of milking frequency (MF) in early lactation have been shown to produce an immediate and a long-term effect on milk yield (MY). The effect is controlled locally within the mammary gland by as yet unknown factors.
Murney, Regan James
core  

Dynamic Contrast Enhanced—Magnetic Resonance Fingerprinting (DCE‐MRF) Improves Detection of Induced Vascular Perfusion Reduction in a Mouse Breast Cancer Model

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Dynamic contrast‐enhanced MRI (DCE‐MRI) can assess tumor perfusion using pharmacokinetic models. However, poor DCE‐MRI reproducibility from reliance on conventional T1‐weighted MRI has limited clinical translation. We evaluated whether Dynamic Contrast Enhanced‐Magnetic Resonance Fingerprinting (DCE‐MRF), which directly generates ...
Christina J. MacAskill, Bernadette O. Erokwu, Yuran Zhu, Guanhua Wang, Andrew Dupuis, Barbara J. Schiemann, Gopalakrishnan Ramamurthy, Chetan B. Dhakan, Michael Kavran, Chunying Wu, William P. Schiemann, Yilun Sun, Mark A. Griswold, Xin Yu, Mark D. Pagel, Chris A. Flask   +15 more
wiley   +1 more source

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

Construction and Identification of a Breast Bioreactor for Human-Derived Hypoglycemic Protein Amylin

Life
The mammary gland of mammals can generate numerous bioactive proteins. To express the human amylin protein in the mammary glands of domestic animals, we engineered a transgenic mammary gland bioreactor. For this study, we produced transgenic mice through
Kongwei Huang, Xiuying Yan, Zhipeng Li, Fuhang Liu, Kuiqing Cui, Qingyou Liu   +5 more
doaj   +1 more source

Interpretable CRAM‑Enhanced Lightweight Dual‑Branch CNN for Real‑Time Breast Cancer Histopathology in Internet‑of‑Medical‑Things Environments

Small, EarlyView.
This study presents an interpretable, lightweight hybrid deep learning model for real‐time analysis of breast cancer histopathology in IoMT‐enabled diagnostic systems. By integrating MobileNetV2 and EfficientNet‐B0 with a novel contextual recurrent attention module (CRAM), the framework achieves near‐perfect accuracy while providing transparent Grad ...
Roseline Oluwaseun Ogundokun, Rotimi‐Williams Bello, Pius Adewale Owolawi, Rytis Maskeliūnas, Abdulsatar Abduljabbar Sultan   +4 more
wiley   +1 more source