Comparison of the biomarkers for targeted therapies in primary extra‐mammary and mammary Paget's disease [PDF]
Cancer Medicine, 2020 Background Primary Extra‐mammary Paget's disease (EMPD) is a very rare cutaneous adenocarcinoma affecting anogenital or axillary regions. It is characterized by a prolonged course with recurrences and eventually distant metastatic spread for which no ...
Zoran Gatalica +11 more
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Mammary Paget's disease occurring after mastectomy [PDF]
World Journal of Surgical Oncology, 2006 Background Mammary Paget's disease and extramammary Paget's disease are neoplastic conditions, in which there is intraepithelial (usually intraepidermal) infiltration by neoplastic cells showing glandular differentiation.
Piubello Quirino +3 more
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Mammary and extramammary Paget's disease [PDF]
Anais Brasileiros de Dermatologia, 2015 Paget's disease, described by Sir James Paget in 1874, is classified as mammary and extramammary. The mammary type is rare and often associated with intraductal cancer (93-100% of cases).
Lauro Lourival Lopes Filho +5 more
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Mammary Paget’s Disease of the Nipple: A Case Report [PDF]
Case Reports in OncologyIntroduction: Tumors of the nipple-areolar complex are relatively uncommon, and Paget’s disease is an uncommon presentation involving epidermal invasion of the nipple by a carcinoma in situ.
Loubna Slama +7 more
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Mammary Paget’s disease in a young woman: A rare occurrence [PDF]
Radiology Case ReportsMammary Paget's disease (MPD) is a rare intraepithelial carcinoma involving the nipple-areolar complex, often linked to underlying ductal carcinoma. We report a case of a 47-year-old woman presenting with progressive swelling of the left nipple, without ...
Chaimae Abourak +9 more
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Mammary Paget’s disease without underlying malignancy of the breast [PDF]
Yeungnam University Journal of Medicine, 2018 Mammary Paget’s disease (MPD) is usually accompanied by underlying breast malignancy; however, a few cases have been reported as only skin lesions without any evidence of malignancy of the breast on imaging tests and microscopic examination of surgical ...
Nuri Jang, Suhwan Kang, Young Kyung Bae
doaj +2 more sources
Reflectance Confocal Microscopy Can Help in Detecting Clinically Silent Mammary Paget’s Disease [PDF]
DiagnosticsEarly detection and comprehensive diagnostic approaches for breast cancer are essential for improving prognosis. When it comes to changes in the skin of the breast or the nipple–areola complex (NAC), particularly if they are unilateral, it is essential ...
Carmen Cantisani +9 more
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Establishment and characterization of breast cancer organoids from a patient with mammary Paget’s disease [PDF]
Cancer Cell International, 2020 Background Mammary Paget’s disease (MPD) is an uncommon cutaneous intraepithelial malignancy with ulceration of the nipple or areola. Its pathogenesis and genomic mutation remain largely unknown and no cell lines are established from primary tumors ...
Bo Pan +8 more
doaj +2 more sources
Significant efficacy of trastuzumab emtansine in HER2-positive relapsed mammary Paget’s disease: a case report and literature review [PDF]
Discover OncologyA 58-year-old female patient was referred to our hospital due to a left chest wall relapse after a surgical excision 20 years ago. She received taxanes and trastuzumab regimen treatment for chest wall recurrence in 2019, but subsequently discontinued the
Weiping Li +7 more
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Case Report: Hidden danger in breast eczematous lesions: cutaneous metastasis from silent lung adenocarcinoma misdiagnosed as Paget’s disease [PDF]
Frontiers in OncologyBackgroundCutaneous metastasis from lung adenocarcinoma is uncommon and may clinically mimic primary dermatologic or breast diseases, particularly when it involves the nipple-areola complex.
Zhenni Gong +15 more
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