Results 31 to 40 of about 4,931,712 (128)

Protocol for stage 2 of the GaP study (genetic testing acceptability for Paget's disease of the bone) : a questionnaire study to investigate whether relatives of people with Paget's disease would accept genetic testing and preventative treatment if they were available [PDF]

open access: yes, 2008
Background: Paget's disease of bone (PDB) disrupts normal bone architecture and causes pain, deformity, deafness, osteoarthritis, and fractures. Genetic factors play a role in PDB and genetic tests are now conducted for research purposes.
Ralston, Stuart H.   +81 more
core   +2 more sources

Intraepidermal malignancy in breast skin: A tale of two tumours

open access: yesHuman Pathology: Case Reports, 2018
Mammary Paget's disease most commonly affects the nipple areolar complex and is frequently associated with an underlying in-situ or invasive breast carcinoma.
Zitong Zhao   +5 more
doaj   +1 more source

Mammary Paget Disease With Melanocytic Proliferation Mimicking Malignant Melanoma in situ: A Case Report

open access: yesFrontiers in Medicine, 2022
Several cases of pigmented mammary Paget’s disease (PMPD) mimicking cutaneous malignant melanoma have been reported. In these cases, the tumor cells are colonized by melanocytes, particularly with the presence of a population of melanocytes staining for ...
Shijia Rao   +7 more
doaj   +1 more source

Paget´s disease of the male breast: An unusual case in a young man and literature review

open access: yesCurrent Problems in Cancer: Case Reports, 2020
Mammary Paget's disease (PD) is characterized by eczematous changes of the nipple-areolar complex and is usually associated with an underlying breast cancer (BC). PD of the breast is rare, comprising about 1–4% of all BC.
Vanesa Rodríguez-Fernández   +7 more
doaj   +1 more source

Not All Cases of Mammary Paget's Disease are Cytokeratin-7 Positive: A Challenging Diagnosis!

open access: yes, 2021
Mammary Paget's disease accounts for 1% to 3% of all breast tumors and manifests as a chronic eczematous lesion of the areolar skin. It can occur without any underlying neoplasia or can be present in association with an underlying invasive and/or in situ
Van Bockstal, Mieke   +4 more
core   +1 more source

Invasive Vulval Paget’s disease treated with primary radiotherapy: A rare case report and literature review

open access: yesGynecologic Oncology Reports, 2020
Extramammary Vulval Paget’s Disease (VPD) is rare neoplasm of post-menopausal women. In relatively young perimenopausal patients, it can cause both diagnostic dilemma and therapeutic challenges. Majority of VPD is of non-invasive variety.
Avir Sarkar   +5 more
doaj   +1 more source

An Unusual Case of Mammary Paget’s Disease Diagnosed Using Dynamic Contrast-Enhanced MRI

open access: yesCase Reports in Radiology, 2013
Mammary Paget’s disease is a rare presentation of breast cancer. At clinical examination, it is characterized by skin lesions of the nipple-areola complex, almost always a sign of malignancy.
Eleonora Gaspari   +5 more
doaj   +1 more source

Doença de Paget pigmentada do mamilo simulando melanoma cutâneo: importância da imuno-histoquímica na diferenciação dessas doenças Pigmented Paget's disease of the nipple mimicking cutaneous melanoma: importance of the immunohistochemical profile to differentiate between these diseases

open access: yesAnais Brasileiros de Dermatologia, 2006
A variante pigmentada da doença de Paget mamária é rara, com cerca de 12 casos relatados, e pode mimetizar clínica e histologicamente o melanoma. Como na forma clássica, em geral associa-se à neoplasia da mama acometida, com origem principalmente no ...
Tatiana Villas Boas Gabbi   +2 more
doaj   +1 more source

Mammary-like adenocarcinoma of the vulva associated to Paget's disease: a case report

open access: yesThe Pan African Medical Journal, 2014
Mammary-like adenocarcinoma of the vulva associated to Paget's disease is exceedingly rare. So, it is very important to perform all the pathological and immunohistochemical investigations to achieve differential diagnosis from both a metastatic lesion ...
Sawsen Meddeb   +6 more
doaj   +1 more source

Frequent expression of the breast differentiation antigen NY-BR-1 in mammary and extramammary Paget's disease [PDF]

open access: yes, 2010
While mammary Paget's disease (MPD) is clearly linked to breast cancer, the histogenesis of extramammary Paget's disease (EMPD) is controversial. Recently NY-BR-1, a differentiation antigen expressed in the breast and in skin adnexal structures was ...
Giger, O   +15 more
core   +1 more source

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