Results 51 to 60 of about 4,931,712 (128)

Paget’s disease of the breast: a contemporary perspective

Исследования и практика в медицине, 2023
The treatment strategy for Paget’s breast cancer (PBC), as for other morphological forms, is determined by the spread of the invasive tumor process, as well as the absence or presence of adverse factors. Significant prognostic factors, e.g.
O. O. Yemelyanova, A. D. Zikiryakhodzhaev, N. N. Volchenko, V. V. Efanov   +3 more
doaj   +1 more source

S1 guideline sweat gland carcinoma

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 9, Page e1356-e1385, September 2026.
Summary The current classification of sweat gland carcinomas is based on histomorphological characteristics and distinguishes between more than 20 entities. Most patients are older, but some subtypes also affect middle‐aged and younger patients. The majority of tumors arise de novo. Sweat gland carcinomas have nonspecific clinical features.
Mirjana Ziemer, Michael Erdmann, Abbas Agaimy, Jürgen C. Becker, Almut Böer‐Auer, Doris Helbig, Cornelia Erfurt‐Berge, Alexander Frisman, Conrad Hempel, Ulrike Leiter, Friedegund Meier, Thomas Mentzel, Lara Racz, Silke Redler, Stefan Schliep, Clemens Seidel, Alpaslan Tasdogan, Jochen Utikal, Carsten Weishaupt, Selma Ugurel   +19 more
wiley   +1 more source

Male Paget's Disease of the Breast

, 2000
Background: Paget's disease is an extremely rare condition of the male breast that presents as an eczematous change of the nipple and areola. It is almost always associated with an underlying intraductal carcinoma. Objective: A case of Paget's disease of
Robert A.W. Miller, Ashim K. Guha, Robert Hayes, Brian Cummings   +3 more
core   +1 more source

Perianal Paget's disease—Report of a rare case [PDF]

, 2012
INTRODUCTIONPerianal extra-mammary Paget's disease is a rare skin disorder of unknown aetiology, which is frequently associated with malignancy. This case report draws attention to this rare condition and comments upon its diagnosis and treatment ...
Stavrou, Maria, Martin, Laura, El-Madani, Faisal, Papanastasiou, Stephanos, Gupta, Sanjay, Naik, Veena   +5 more
core   +1 more source

Mammary Paget's disease

, 2011
peer reviewedMammary Paget's disease is an intraepithelial carcinoma present on the nipple and its areola. The tumor typically develops in middle aged women. It is frequently associated or contiguous to an underlying galactophoric adenocarcinoma.
PIERARD, Gérald, QUATRESOOZ, Pascale, PIERARD-FRANCHIMONT, Claudine, REGINSTER, Marie-Annick   +3 more
core   +1 more source

Reflectance confocal microscopy for diagnosis of mammary and extramammary Paget's disease

, 2013
Background Paget's disease is an intraepidermal adenocarcinoma that is difficult to diagnose clinically as it mimics inflammatory or infectious diseases.
Guitera, P, Arima, M., Gill, M., PELLACANI, Giovanni, LONGO, Caterina, Matsunaga, K., Akita, H., Alessi Fox, C., Bassoli, S., Bencini, P. L., Scolyer, R. A., Giannotti, R., Yokoyama, Y., Dalrymple, C.   +13 more
core   +1 more source

Mammary Fibroblasts Secrete Damage Associated Molecular Patterns Through Extracellular Vesicles in Response to Ionizing Radiation

Journal of Extracellular Biology, Volume 5, Issue 5, May 2026.
We show that ionizing radiation (IR)‐induced damage in mammary fibroblasts results in a senescence‐like phenotype including enhanced EV and cytokine secretion. Proteomic profiling revealed that IR‐induced EVs are enriched with damage associated molecular patterns (DAMPs) and pro‐inflammatory mediators.
Greg Berumen Sánchez, Purvi Patel, Preston Gomez‐Crase, Chloe Kim, Kevin C. Corn, Kristie L. Rose, Marjan Rafat   +6 more
wiley   +1 more source

Treatment of Paget’s Disease of Bone

, 2016
Paget's disease involves overactivity of both osteoblasts and osteoclasts within affected bone tissue. It is unclear in which cells the causative lesion resides, but therapies have generally been antiosteoclastic (antiresorptive) because these are the ...
Reid, Ian, Ian R. Reid
core   +1 more source

Murine amniotic fluid stem cells contribute mesenchymal but not epithelial components to reconstituted mammary ducts [PDF]

, 2010
Introduction: Amniotic fluid harbors cells indicative of all three germ layers, and pluripotent fetal amniotic fluid stem cells (AFSs) are considered potentially valuable for applications in cellular therapy and tissue engineering.
Bernd Groner, Vafaizadeh, Vida, Groner, Bernd, Petra AB Klemmt, Vida Vafaizadeh, Klemmt, Petra A. B.   +5 more
core   +1 more source

Rescuing Mitochondrial Dysfunction in Macrophages Prevents Osteonecrosis of the Jaw in Anti‐Resorptive Therapy

Advanced Science, Volume 13, Issue 11, 23 February 2026.
Schematic model showing the suggested mechanism that ZA induces classical activation of macrophages by impairing mitochondrial biofunction and inhibiting mitochondrial clearance to contribute to the pathological process of BRONJ. RAPA‐loaded nanoparticles ZDPR has shown potential in alleviating BRONJ lesions as well as treating osteoporosis or ...
Hang Zhang, Xin Shen, Haiyang Liu, Xinxi Yuan, Mumin Cao, Xuepeng Lv, Ziji Ling, Songsong Guo, Rongyao Xu, Xiang Li, Hongbing Jiang   +10 more
wiley   +1 more source