Dietary calcium and vitamin D intakes in childhood and throughout adulthood and mammographic density in a British birth cohort. [PDF]
We examined the role of dietary calcium and vitamin D intakes in childhood and throughout adulthood in relation to mammographic density using data from a nationally representative cohort of 1161 women followed up since their birth in 1946.
Hardy, R +18 more
core +1 more source
Area and volumetric density estimation in processed full-field digital mammograms for risk assessment of breast cancer. [PDF]
INTRODUCTION: Mammographic density, the white radiolucent part of a mammogram, is a marker of breast cancer risk and mammographic sensitivity. There are several means of measuring mammographic density, among which are area-based and volumetric-based ...
Abbas Cheddad +6 more
doaj +1 more source
Genetic determinants of mammographic density [PDF]
Changes in breast density are highly correlated with steroid hormone exposure.In a cross-sectional study of 396 Caucasian and African-American women, we evaluated whether polymorphisms in genes involved in steroid hormone biosynthesis and metabolism, CYP17 (T27C), COMT (Val158Met), 17HSDB1 (Ser312Gly) and 3HSDB1 (Asn367Thr), predict mammographic ...
Haiman, Christopher A +5 more
openaire +4 more sources
Ionizing radiation and volumetric mammographic density
Mammographic density (MD) refers to the percentage of dense tissue of an entire breast and was proposed to be used as a surrogate marker for breast cancer. High-dose ionizing radiation (IR) has been recognized as a breast cancer risk factor. The aim of our study was to investigate association between lifetime low dose ionizing radiation (LDIR) and MD.A
Beata Pepłońska +3 more
openaire +3 more sources
Energy intake and dietary patterns in childhood and throughout adulthood and mammographic density: results from a British prospective cohort. [PDF]
OBJECTIVES: To examine the role of energy intake and dietary patterns in childhood and throughout adulthood on subsequent mammographic density. METHODS: Prospective data were available from a cohort of 1161 British women followed up since their birth in ...
Isabel dos Santos Silva +17 more
core +1 more source
Immune Regulation of Mammary Fibroblasts and the Impact of Mammographic Density [PDF]
Mammographic density is associated with a 4-6-fold increase in breast cancer risk independent of age and BMI. High mammographic density is characterized by breast tissue with high proportions of stroma comprised of fibroblasts, collagen, and immune cells.
Dasari, P +5 more
core +2 more sources
Mammographic density and molecular subtypes of breast cancer. [PDF]
BACKGROUND: Gene expression profiling has led to a subclassification of breast cancers independent of established clinical parameters, such as the Sorlie-Perou subtypes.
Bergh, J +21 more
core +1 more source
Life-course body size and perimenopausal mammographic parenchymal patterns in the MRC 1946 British birth cohort. [PDF]
Dense mammographic parenchymal patterns are associated with an increased risk of breast cancer. Certain features of body size have been found to be associated with breast cancer risk, but less is known about their relation to breast density.
Swerdlow, AJ +18 more
core +1 more source
Mammographic density, blood telomere length and lipid peroxidation
Extensive mammographic density is a strong risk factor for breast cancer, but may also be an indicator of biological age. In this study we examined whether mammographic density is related to blood telomere length, a potential marker of susceptibility to ...
Natalie J. Erdmann +2 more
doaj +1 more source
Introduction Using mammographic density as a significant biomarker for predicting prognosis in adjuvant hormone therapy patients is controversial due to the conflicting results of recent studies.
Wei-Chung Shia PhD +4 more
doaj +1 more source

