Results 51 to 60 of about 4,902 (181)

Organoid‐based novel technology for antitumor drug screening

VIEW, Volume 6, Issue 6, December 2025.
Organoids represent a cutting‐edge research model that closely mimics in vivo organ physiology, making them highly valuable for tumor immunotherapy drug screening. This review explores the integration of organoids with advanced technologies, such as gene editing, 3D bioprinting, and AI, highlighting novel fusion platforms and their applications.
Yu Su, Yuan Chen, Guanning Wei, Yihai Shi   +3 more
wiley   +1 more source

Case report: tuberous breast [PDF]

Revista Brasileira de Cirurgia Plástica, 2017
To report a case of tuberous breast with significant breast asymmetry, describe the technique used and evaluate the outcome of the case. Different techniques were used on each breast, although studies in literature recommend the use of similar strategy ...
Tulio Martins Silva, Bianca Maria Barros Ohana, Bruno Perrelli Sá Freire Fernandes, Irene Daher Barra, Maria Alice Domingues Rezende, Celso Eduardo Jandre Boechat   +5 more
doaj   +1 more source

Sensitization Patterns to Cyanoacrylate‐Based Surgical Glues

Contact Dermatitis, Volume 93, Issue 4, Page 328-335, October 2025.
Surgical glues are increasingly used posing risks of allergic contact dermatitis caused by cyanoacrylate monomers. Ethyl cyanoacrylate (ECA) and surgical glues « as is » testing has proven to be a good tool for Patch test in sensitised patients. ABSTRACT Background Surgical glues are increasingly used, offering advantages like reduced scarring and ...
Lucrezia Bianchetti, Anna Walker, Ophelie Marchal, Laura Bruschi, Héloïse Wüthrich, An Goossens, Ella Dendooven, Olivier Aerts, Curdin Conrad, Michel Gilliet, Teofila Seremet   +10 more
wiley   +1 more source

Freestyle Perforator Flap Based Reduction Mammoplasty According to Dominant Perforator Determined by Handheld Doppler US (Benha University Study)

Egyptian Journal of Plastic and Reconstructive Surgery
Background: Breast hypertrophy may cause physical and psychological distress, and reduction mammoplasty is the treatment of choice. However, variations in vascular anatomy predispose to Nipple–Areola Complex (NAC) complications as necrosis.
Ahmed Mahmoud Ahmed, Gamal Elhabaa, Ahmed Shoulah, Mohamed Abdelhalim, Ola Seif   +4 more
doaj   +1 more source

Skin-reducing mastectomy using inferior pedicle dermal fat flaps in immediate reconstruction of medium and large hypertrophic breasts [PDF]

Revista Brasileira de Cirurgia Plástica, 2017
INTRODUCTION: Breast cancer is the most common type of neoplasm among women (except for non-melanoma skin cancers), and in the past few years, its treatment greatly evolved with skin-sparing mastectomies.
Francisco Felipe Laitano
doaj   +1 more source

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, Volume 19, Issue 9, Page 2557-2573, September 2025.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source

Requirements for Alternative In Vitro and In Silico Skin Models of Irritant and Allergic Contact Dermatitis

Contact Dermatitis, Volume 93, Issue 3, Page 187-203, September 2025.
ABSTRACT Contact dermatitis is an inflammatory disease characterised by skin redness and swelling, oozing of fluid or pus and pain, caused by direct skin contact with an irritant or allergen. Its prevalence has skyrocketed worldwide, probably because human skin is in daily contact with an increasing gamut of irritants and allergens, which should ...
Meital Portugal‐Cohen, Warangkana Lohcharoenkal, Evelyn Kelemen, Inge Kortekaas Krohn, Shauni De Vriese, Danuta Gutowska‐Owsiak, Ivone Jakasa, Dijana Furundžić, Anna Zalewska‐Janowska, Sandrine Dubrac   +9 more
wiley   +1 more source

Cryopreserved Total Skin Allografts From Living Donors for Complex Wound Management: A New Paradigm in Regenerative Wound Care

International Wound Journal, Volume 22, Issue 9, September 2025.
ABSTRACT Skin allografts are essential in managing complex wounds, yet their availability is limited by low post‐mortem donation rates. Skin harvested during body contouring surgeries offers a novel and sustainable source to expand tissue supply. We conducted a retrospective descriptive study at the Tarapacá Skin and Tissue Bank from January 2022 to ...
Marcelo Fonseca, Aldo Cañete, Luana Mandriaza, Jennifer Gómez, Jaume Masiá, Katherine Marcelain, Dino Ibaceta, Cristian Erazo, Brenda Gámez, Monserrat Rius, Florencia Disi   +10 more
wiley   +1 more source

Characteristics of histiocytic neoplasms presenting as breast masses

British Journal of Haematology, Volume 208, Issue 1, Page 358-362, January 2026.
Theodore Vougiouklakis, Marc K. Rosenblum, Matthew Cannavo, Kimberly Feigin, Andrew E. Rosenberg, Frederick Wittlin, Sonia Mahajan, Edi Brogi, Maria E. Arcila, Hannah Y. Wen, Eli L. Diamond   +10 more
wiley   +1 more source

Effect of Topical Timolol on Healing of Immature Breast Scars After Mammoplasty: A Randomized Controlled Trial With Blinded Assessors and Patients

Journal of Cosmetic Dermatology, Volume 24, Issue 6, June 2025.
ABSTRACT Introduction Wound healing is a complex process encompassing four main stages: hemostasis, inflammation, cell proliferation, maturation, and differentiation. Timolol (TM) may influence these stages, particularly re‐epithelialization. This study aims to evaluate the 1‐month effects of timolol on acute surgical wounds in post‐mammoplasty ...
Nahid Nafissi, Fatemeh Najafi, Alireza Jafarzadeh, Elham Behrangi, Masoumeh Roohaninasab, Seyyedeh Tahereh Rahimi, Sepideh Salehi, Amir Jafari‐Nasirmahalleh, Nazanin Hoseini, Azadeh Goodarzi   +9 more
wiley   +1 more source