Results 61 to 70 of about 4,768 (181)

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, Volume 19, Issue 9, Page 2557-2573, September 2025.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source

Mapping genomic and transcriptomic alterations spatially in epithelial cells adjacent to human breast carcinoma. [PDF]

, 2017
Almost all genomic studies of breast cancer have focused on well-established tumours because it is technically challenging to study the earliest mutational events occurring in human breast epithelial cells.
Abdalla, Mohamed, Abdalla, Moustafa, Arneson, Nona, Boutros, Paul C, Cawthorn, Thomas R, Done, Susan J, Easson, Alexandra M, Fox, Natalie S, Iakovlev, Vladimir, Kanwar, Nisha, Kwan, Jennifer Yin Yee, Lee, Jennifer PY, Leong, Wey L, McCready, David, Miller, Naomi A, Moreno, Juan, Nair, Ranju, Tran-Thanh, Danh, Wang, Dong-Yu, Warren, Keisha, Youngson, Bruce J   +20 more
core   +2 more sources

Requirements for Alternative In Vitro and In Silico Skin Models of Irritant and Allergic Contact Dermatitis

Contact Dermatitis, Volume 93, Issue 3, Page 187-203, September 2025.
ABSTRACT Contact dermatitis is an inflammatory disease characterised by skin redness and swelling, oozing of fluid or pus and pain, caused by direct skin contact with an irritant or allergen. Its prevalence has skyrocketed worldwide, probably because human skin is in daily contact with an increasing gamut of irritants and allergens, which should ...
Meital Portugal‐Cohen, Warangkana Lohcharoenkal, Evelyn Kelemen, Inge Kortekaas Krohn, Shauni De Vriese, Danuta Gutowska‐Owsiak, Ivone Jakasa, Dijana Furundžić, Anna Zalewska‐Janowska, Sandrine Dubrac   +9 more
wiley   +1 more source

Постимплантационный полиакриламидный маммарный синдром: актуальная проблема общехирургических стационаров [PDF]

, 2016
МОЛОЧНОЙ ЖЕЛЕЗЫ ПЛАСТИКАКОСМЕТИЧЕСКИЕ ДЕФЕКТЫСИЛИКОНОВЫЕ ЭНДОПРОТЕЗЫПОЛИАКРИЛАМИДНЫЙ ГЕЛЬПАТОЛОГИЧЕСКИЕ ПРОЦЕССЫПОСТИМПЛАНТАЦИОННЫЙ ПОЛИАКРИЛАМИДНЫЙ МАММАРНЫЙ СИНДРОМРЕЗУЛЬТАТЫ ...
Комарова, Е. А., Липатов, К. В., Насибов, Б. Ш., Стручков, Ю. В.   +3 more
core  

Cryopreserved Total Skin Allografts From Living Donors for Complex Wound Management: A New Paradigm in Regenerative Wound Care

International Wound Journal, Volume 22, Issue 9, September 2025.
ABSTRACT Skin allografts are essential in managing complex wounds, yet their availability is limited by low post‐mortem donation rates. Skin harvested during body contouring surgeries offers a novel and sustainable source to expand tissue supply. We conducted a retrospective descriptive study at the Tarapacá Skin and Tissue Bank from January 2022 to ...
Marcelo Fonseca, Aldo Cañete, Luana Mandriaza, Jennifer Gómez, Jaume Masiá, Katherine Marcelain, Dino Ibaceta, Cristian Erazo, Brenda Gámez, Monserrat Rius, Florencia Disi   +10 more
wiley   +1 more source

Oncoplastic central quadrantectomies [PDF]

, 2016
Tumors localized in the central quadrant (centrally located breast tumors) have always represented a challenge for the surgeon because of the critical aesthetical matters related to the nipple-areola complex (NAC).
AMABILE, MARIA IDA, Buè, Rosanna, D'ORAZI, VALERIO, DE LUCA, ALESSANDRO, FRUSONE, FEDERICO, MEROLA, RAFFAELE, MONTI, Marco, PASTA, Vittorio   +7 more
core   +1 more source

Effect of Topical Timolol on Healing of Immature Breast Scars After Mammoplasty: A Randomized Controlled Trial With Blinded Assessors and Patients

Journal of Cosmetic Dermatology, Volume 24, Issue 6, June 2025.
ABSTRACT Introduction Wound healing is a complex process encompassing four main stages: hemostasis, inflammation, cell proliferation, maturation, and differentiation. Timolol (TM) may influence these stages, particularly re‐epithelialization. This study aims to evaluate the 1‐month effects of timolol on acute surgical wounds in post‐mammoplasty ...
Nahid Nafissi, Fatemeh Najafi, Alireza Jafarzadeh, Elham Behrangi, Masoumeh Roohaninasab, Seyyedeh Tahereh Rahimi, Sepideh Salehi, Amir Jafari‐Nasirmahalleh, Nazanin Hoseini, Azadeh Goodarzi   +9 more
wiley   +1 more source

Male, Female, Other: Transgender and the Impact in Primary Care [PDF]

, 2016
Transgender includes patients at various stages of their journey. It is important that providers care for transgender patients with a culturally sensitive approach, awareness, and competent skill. There are new terms to learn.
Markwick, Laura
core   +2 more sources

Breast Reconstruction After Mastectomy Using a Deep Inferior Epigastric Perforator (DIEP) Flap: Clinical and Medico‐Legal Insights From a Four‐Year Study

Health Science Reports, Volume 8, Issue 4, April 2025.
ABSTRACT Aims Breast reconstruction after mastectomy is nowadays a gold standard in therapy of breast cancer patients. Free deep inferior epigastric perforator (DIEP) flap reconstruction is a favorable method when traditional implants fail or are not viable, especially after radiotherapy. The aim of this paper is to present the results of a case series
Demetris Savva, Giulio Nittari, Filippo Gibelli, Giovanna Ricci, Savvas Dalitis, Antonia Fotiou, Phanos Michael   +6 more
wiley   +1 more source

Characteristics of histiocytic neoplasms presenting as breast masses

British Journal of Haematology, Volume 208, Issue 1, Page 358-362, January 2026.
Theodore Vougiouklakis, Marc K. Rosenblum, Matthew Cannavo, Kimberly Feigin, Andrew E. Rosenberg, Frederick Wittlin, Sonia Mahajan, Edi Brogi, Maria E. Arcila, Hannah Y. Wen, Eli L. Diamond   +10 more
wiley   +1 more source